HIPK4 Antibody (PACO15650)
- SKU:
- PACO15650
- Product Type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- ELISA
- Applications:
- IHC
- Antibody Type:
- Polyclonal Antibody
- Conjugation:
- Unconjugated
Description
| Antibody Name: | HIPK4 Antibody (PACO15650) |
| Antibody SKU: | PACO15650 |
| Size: | 50ul |
| Host Species: | Rabbit |
| Tested Applications: | ELISA, IHC |
| Recommended Dilutions: | ELISA:1:2000-1:5000, IHC:1:25-1:100 |
| Species Reactivity: | Human, Mouse, Rat |
| Immunogen: | Fusion protein of human HIPK4 |
| Form: | Liquid |
| Storage Buffer: | -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol |
| Purification Method: | Antigen affinity purification |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
 | The image on the left is immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using PACO15650(HIPK4 Antibody) at dilution 1/40, on the right is treated with fusion protein. (Original magnification: x200). |
| Background: | HIPK4 (Homeodomain-interacting protein kinase 4) is a 616 amino acid, protein that localizes to the cytoplasm and exists as two isoforms that are produced by alternative splicing events. Like other members of the HIPK family, HIPK4 functions as a protein kinase that catalyzes the ATP-dependent phosphorylation of target proteins and is thought to act as a corepressor of target transcription factors. |
| Synonyms: | homeodomain interacting protein kinase 4 |
| UniProt Protein Function: | HIPK4: a CMGC kinase of the DYRK family.Protein type: EC 2.7.11.1; Protein kinase, CMGC; Kinase, protein; Protein kinase, Ser/Thr (non-receptor); CMGC group; DYRK family; HIPK subfamilyChromosomal Location of Human Ortholog: 19q13.2Molecular Function: protein binding |
| UniProt Protein Details: | |
| NCBI Summary: | This gene encodes a member of the homeodomain interacting protein kinase (HIPK) family of proteins. While other members of this family are found throughout vertebrates, this member is present only in mammals. Compared to other members of this family, the encoded protein lacks a nuclear localization signal and a C-terminal autoinhibitory domain. The encoded protein exhibits kinase activity and may phosphorylate the tumor suppressor protein p53. [provided by RefSeq, Jul 2016] |
| UniProt Code: | Q8NE63 |
| NCBI GenInfo Identifier: | 74762559 |
| NCBI Gene ID: | 147746 |
| NCBI Accession: | Q8NE63.1 |
| UniProt Secondary Accession: | Q8NE63,Q96M54, A8K863 |
| UniProt Related Accession: | Q8NE63 |
| Molecular Weight: | 69,425 Da |
| NCBI Full Name: | Homeodomain-interacting protein kinase 4 |
| NCBI Synonym Full Names: | homeodomain interacting protein kinase 4 |
| NCBI Official Symbol: | HIPK4 |
| NCBI Official Synonym Symbols: | |
| NCBI Protein Information: | homeodomain-interacting protein kinase 4 |
| UniProt Protein Name: | Homeodomain-interacting protein kinase 4 |
| UniProt Synonym Protein Names: | |
| Protein Family: | Homeodomain-interacting protein kinase |
| UniProt Gene Name: | HIPK4 |
| UniProt Entry Name: | HIPK4_HUMAN |
| Antibodies |
| HIPK4 Antibody (PACO00906) |
| Secondary Antibody |
| Anti-HRP Goat Anti-Rabbit IgG (H+L) Antibody (CABS014) |
| Recommended Products |
| Anti-FITC Goat Anti-Rabbit IgG (H+L) Antibody (CABS011) |
| Anti-HRP-conjugated Beta Actin Antibody (CABC028) |
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