Name: HID1 Antibody (PACO19502)
SKU: PACO19502
Availability: OutOfStock

Antibody Name:	HID1 Antibody (PACO19502)
Antibody SKU:	PACO19502
Size:	50ul
Host Species:	Rabbit
Tested Applications:	ELISA, IHC
Recommended Dilutions:	ELISA:1:2000-1:5000, IHC:1:25-1:100
Species Reactivity:	Human, Mouse
Immunogen:	Synthetic peptide of human HID1

Form:	Liquid
Storage Buffer:	-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
Purification Method:	Antigen affinity purification
Clonality:	Polyclonal
Isotype:	IgG
Conjugate:	Non-conjugated

The image on the left is immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using PACO19502(HID1 Antibody) at dilution 1/50, on the right is treated with synthetic peptide. (Original magnification: x200).

Background:

C17orf28 (chromosome 17 open reading frame 28) is a 788 amino acid, multi-pass membrane protein that is expressed in heart, skeletal muscle, colon, spleen, kidney, liver, small intestine and lung. C17orf28 may be involved in the development of cancers in a broad range of tissues. Existing as three alternatively spliced isoforms, C17orf28 is encoded by a gene mapping to human chromosome 17, which makes up over 2.5% of the human genome with about 81 million bases encoding over 1,200 genes. Two key tumor suppressor genes are associated with chromosome 17, namely, p53 and BRCA1.

Synonyms:

HID1 domain containing

UniProt Protein Function:	HID1: May play an important role in the development of cancers in a broad range of tissues. Belongs to the hid-1 family. 3 isoforms of the human protein are produced by alternative splicing.Protein type: Membrane protein, integral; DNA-bindingChromosomal Location of Human Ortholog: 17q25.1Cellular Component: cytoplasm; cytoplasmic microtubule; Golgi apparatus; Golgi medial cisterna; Golgi trans cisternaMolecular Function: protein bindingBiological Process: intracellular protein transport; response to brefeldin A
UniProt Protein Details:
NCBI Summary:
UniProt Code:	Q8IV36
NCBI GenInfo Identifier:	68565199
NCBI Gene ID:	283987
NCBI Accession:	Q8IV36.1
UniProt Secondary Accession:	Q8IV36,Q8N5L6, Q8TE83, Q9NT34
UniProt Related Accession:	Q8IV36
Molecular Weight:	63,245 Da
NCBI Full Name:	Protein HID1
NCBI Synonym Full Names:	HID1 domain containing
NCBI Official Symbol:	HID1
NCBI Official Synonym Symbols:	DMC1; HID-1; C17orf28
NCBI Protein Information:	protein HID1
UniProt Protein Name:	Protein HID1
UniProt Synonym Protein Names:	Down-regulated in multiple cancers 1; HID1 domain-containing protein; Protein hid-1 homolog
Protein Family:	Protein
UniProt Gene Name:	HID1
UniProt Entry Name:	HID1_HUMAN