Hexokinase II Monoclonal Antibody

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SKU:
CAB22319
Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Reactivity:
Human
Reactivity:
Mouse
Reactivity:
Rat
Host Species:
Rabbit
Isotype:
IgG
Applications:
WB

Description

Product Name:Hexokinase II Monoclonal Antibody
Product Code:CAB22319
Reactivity:Human, Mouse, Rat
Applications:Western blotting
Host Species:Rabbit
Purification Method:Affinity purification
Isotype:IgG
Clone No:ARC52057
Reactivity:Human, Mouse, Rat
Tested Applications:WB, ELISA
Key Applications:Western blotting
Recommended Dilution:WB 1:500-1:1000
Storage Buffer:Store at -20°C. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300, 0.05% BSA, 50% glycerol, pH7.3.
Positive Samples:HeLa, SH-SY5Y, Mouse heart, Rat skeletal muscle
Cellular Location:Mitochondrion outer membrane, Cytoplasm, cytosol

Hexokinases phosphorylate glucose to produce glucose-6-phosphate, the first step in most glucose metabolism pathways. This gene encodes hexokinase 2, the predominant form found in skeletal muscle. It localizes to the outer membrane of mitochondria. Expression of this gene is insulin-responsive, and studies in rat suggest that it is involved in the increased rate of glycolysis seen in rapidly growing cancer cells.

Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 1-120 of human Hexokinase II (NP_000180.2).
Sequence:MIASH LLAYF FTELN HDQVQ KVDQY LYHMR LSDET LLEIS KRFRK EMEKG LGATT HPTAA VKMLP TFVRS TPDGT EHGEF LALDL GGTNF RVLWV KVTDN GLQKV EMENQ IYAIP EDIMR
Synonyms:HKII, HXK2
Calculated MW:102kDa
Observed MW:102kDa
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