Description
system_update_alt Datasheet
Product Name: | HEXA Antibody |
Product Sku: | CPAB0176 |
Size: | 5μg |
Host Species: | Mouse |
Immunogen: | Anti-human HEXA mAb, clone PAT2F1A, is derived from hybridization of mouse F myeloma cells with spleen cells from BALB/c mice immunized with a recombinant human HEXA protein 89-529 amino acids purified from Ecoli. |
Clone: | PAT20F1A. |
Reactivity: | Human |
Applications: | Western Blot, ELISA |
Purification Method: | HEXA antibody was purified by protein-A affinity chromatography. |
Isotype: | IgG2a |
Background: | HEXA is the alpha subunit of the lysosomal enzyme beta-hexosaminidase which, combined with the cofactor GM2 activator protein, catalyzes the degradation of the ganglioside GM2, and other molecules having N-acetyl hexosamines terminus. The two subunits composing Beta-hexosaminidase, alpha and beta, belong to the glycosyl hydrolases family and are encoded by distinct genes. Alpha subunit gene mutations can cause Tay-Sachs disease (GM2-gangliosidosis type I). |
Synonyms: | TSD, hexosaminidase A, Beta-hexosaminidase subunit alpha, Beta-N-acetylhexosaminidase subunit alpha, Hexosaminidase subunit A, N-acetyl-beta-glucosaminidase subunit alpha. |
Storage Buffer: | For periods up to 1 month store at 4°C, for longer periods of time, store at -20°C. Prevent freeze thaw cycles. |