HERC4 Polyclonal Antibody
- SKU:
- CAB21427
- Product Type:
- Antibody
- Antibody Type:
- Polyclonal Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- WB
Description
| Product Name: | HERC4 Polyclonal Antibody |
| Product Code: | CAB21427 |
| Reactivity: | Human |
| Applications: | Western blotting |
| Host Species: | Rabbit |
| Purification Method: | Affinity purification |
| Isotype: | IgG |
| Reactivity: | Human |
| Tested Applications: | WB, ELISA |
| Key Applications: | Western blotting |
| Recommended Dilution: | WB 1:500-1:2000 |
| Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal, 50% glycerol, pH7.3. |
| Cellular Location: | Cytoplasm, cytosol |
HERC4 belongs to the HERC family of ubiquitin ligases, all of which contain a HECT domain and at least 1 RCC1 (MIM 179710)-like domain (RLD). The 350-amino acid HECT domain is predicted to catalyze the formation of a thioester with ubiquitin before transferring it to a substrate, and the RLD is predicted to act as a guanine nucleotide exchange factor for small G proteins (Hochrainer et al., 2005 [PubMed 15676274]).
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 400-700 of human HERC4 (NP_056416.2). |
| Sequence: | WTVNE ALIQK WLSYP SGRFP VEIAN EIDGT FSSSG CLNGS FLAVS NDDHY RTGTR FSGVD MNAAR LLFHK LIQPD HPQIS QQVAA SLEKN LIPKL TSSLP DVEAL RFYLT LPECP LMSDS NNFTT IAIPF GTALV NLEKA PLKVL ENWWS VLEPP LFLKI VELFK EVVVH LLKLY KIGIP PSERR IFNSF LHTAL KVLEI LHRVN EKMGQ IIQYD KFYIH EVQEL IDIRN DYINW VQQQA YGMLA DIPVT ICTYP FVFDA QAKTT LLQTD AVLQM QMAID QAHRQ NVSSL FLPVI ESVNP C |
| Synonyms: | HERC4, probable E3 ubiquitin-protein ligase HERC4 |
| Calculated MW: | 119kDa |
| Observed MW: | Refer to figures |
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