HEPACAM2 Antibody (PACO27349)
- SKU:
- PACO27349
- Product Type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- ELISA
- Applications:
- IHC
- Antibody Type:
- Polyclonal Antibody
- Conjugation:
- Unconjugated
Description
| Antibody Name: | HEPACAM2 Antibody (PACO27349) |
| Antibody SKU: | PACO27349 |
| Size: | 50ug |
| Host Species: | Rabbit |
| Tested Applications: | ELISA, IHC |
| Recommended Dilutions: | ELISA:1:2000-1:10000, IHC:1:20-1:200 |
| Species Reactivity: | Human |
| Immunogen: | Recombinant Human HEPACAM family member 2 protein (32-351AA) |
| Form: | Liquid |
| Storage Buffer: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 |
| Purification Method: | >95%, Protein G purified |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
 | Immunohistochemistry of paraffin-embedded human liver cancer using PACO27349 at dilution of 1:100. |
| Background: | Required during prometaphase for centrosome maturation. Following poly-ADP-ribosylation (PARsylation) by TNKS, translocates from the Golgi apparatus to mitotic centrosomes and plays a key role in the formation of robust microtubules for prompt movement of chromosomes: anchors AKAP9/CG-NAP, a scaffold protein of the gamma-tubulin ring complex and promotes centrosome maturation. |
| Synonyms: | HEPACAM family member 2 (Mitotic kinetics regulator), HEPACAM2, MIKI |
| UniProt Protein Function: | HEPACAM2: Required during prometaphase for centrosome maturation. Following poly-ADP-ribosylation (PARsylation) by TNKS, translocates from the Golgi apparatus to mitotic centrosomes and plays a key role in the formation of robust microtubules for prompt movement of chromosomes: anchors AKAP9/CG-NAP, a scaffold protein of the gamma-tubulin ring complex and promotes centrosome maturation. 3 isoforms of the human protein are produced by alternative splicing.Protein type: Membrane protein, integralChromosomal Location of Human Ortholog: 7q21.3Cellular Component: centrosome; Golgi apparatus; midbody; spindleMolecular Function: protein bindingBiological Process: centrosome organization and biogenesis |
| UniProt Protein Details: | |
| NCBI Summary: | |
| UniProt Code: | A8MVW5 |
| NCBI GenInfo Identifier: | 187659944 |
| NCBI Gene ID: | 253012 |
| NCBI Accession: | A8MVW5.1 |
| UniProt Secondary Accession: | A8MVW5,Q6UXI0, B3KTT4, B4DPJ1, B9EG93, E9PDV5 |
| UniProt Related Accession: | A8MVW5 |
| Molecular Weight: | 54,115 Da |
| NCBI Full Name: | HEPACAM family member 2 |
| NCBI Synonym Full Names: | HEPACAM family member 2 |
| NCBI Official Symbol: | HEPACAM2 |
| NCBI Official Synonym Symbols: | MIKI |
| NCBI Protein Information: | HEPACAM family member 2 |
| UniProt Protein Name: | HEPACAM family member 2 |
| UniProt Synonym Protein Names: | Mitotic kinetics regulator |
| Protein Family: | HEPACAM family |
| UniProt Gene Name: | HEPACAM2 |
| UniProt Entry Name: | HECA2_HUMAN |
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