Description
Product Name: | Heme Oxygenase 1 (HO-1/HMOX1) Polyclonal Antibody |
Product Code: | CAB21452 |
Reactivity: | Human, Mouse, Rat |
Applications: | Western blotting, Immunofluorescence |
Host Species: | Rabbit |
Purification Method: | Affinity purification |
Isotype: | IgG |
Reactivity: | Human, Mouse, Rat |
Tested Applications: | WB, IF/ICC, ELISA |
Key Applications: | Western blotting, Immunofluorescence |
Recommended Dilution: | WB 1:500-1:1000, IF/ICC 1:50-1:200 |
Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300, 50% glycerol, pH7.3. |
Positive Samples: | HeLa, HepG2 |
Cellular Location: | Cytoplasmic side, Endoplasmic reticulum membrane, Microsome, Peripheral membrane protein |
Heme oxygenase, an essential enzyme in heme catabolism, cleaves heme to form biliverdin, which is subsequently converted to bilirubin by biliverdin reductase, and carbon monoxide, a putative neurotransmitter. Heme oxygenase activity is induced by its substrate heme and by various nonheme substances. Heme oxygenase occurs as 2 isozymes, an inducible heme oxygenase-1 and a constitutive heme oxygenase-2. HMOX1 and HMOX2 belong to the heme oxygenase family.
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-288 of human Heme Oxygenase 1 (HO-1/HMOX1) (NP_002124.1). |
Sequence: | MERPQ PDSMP QDLSE ALKEA TKEVH TQAEN AEFMR NFQKG QVTRD GFKLV MASLY HIYVA LEEEI ERNKE SPVFA PVYFP EELHR KAALE QDLAF WYGPR WQEVI PYTPA MQRYV KRLHE VGRTE PELLV AHAYT RYLGD LSGGQ VLKKI AQKAL DLPSS GEGLA FFTFP NIASA TKFKQ LYRSR MNSLE MTPAV RQRVI EEAKT AFLLN IQLFE ELQEL LTHDT KDQSP SRAPG LRQRA SNKVQ DSAPV ETPRG KPPLN TRSQA PLLRW VLTLS FLVAT VAVGL YAM |
Synonyms: | HO-1, HSP32, HMOX1D, bK286B10 |
Calculated MW: | 33kDa |
Observed MW: | 33kDa |