HELZ2 Antibody (PACO05571)
- SKU:
- PACO05571
- Product Type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- ELISA
- Applications:
- WB
- Antibody Type:
- Polyclonal Antibody
- Conjugation:
- Unconjugated
Description
| Antibody Name: | HELZ2 Antibody (PACO05571) |
| Antibody SKU: | PACO05571 |
| Size: | 50ug |
| Host Species: | Rabbit |
| Tested Applications: | ELISA, WB |
| Recommended Dilutions: | ELISA:1:20000, WB:1:500-1:2000 |
| Species Reactivity: | Human |
| Immunogen: | Synthesized peptide derived from the Internal region of human PRIC285. |
| Form: | Liquid |
| Storage Buffer: | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Purification Method: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
| Synonyms: | PRIC285; KIAA1769; Peroxisomal proliferator-activated receptor A-interacting complex 285 kDa protein; ATP-dependent helicase PRIC285; PPAR-α-interacting complex protein 285; PPAR-γ DNA-binding domain-interacting protein 1; PDIP1; PP |
| UniProt Protein Function: | PRIC285: Helicase that acts as a transcriptional coactivator for a number of nuclear receptors including PPARA, PPARG, THRA, THRB and RXRA. Belongs to the DNA2/NAM7 helicase family. 3 isoforms of the human protein are produced by alternative splicing.Protein type: C2H2-type zinc finger protein; EC 3.6.4.-; Transcription, coactivator/corepressor; Nuclear receptor co-regulator; EC 3.6.1.-; HelicaseChromosomal Location of Human Ortholog: 20q13.33Cellular Component: nucleoplasm; membraneMolecular Function: protein binding; DNA binding; ligand-dependent nuclear receptor transcription coactivator activity; metal ion binding; helicase activity; ATP bindingBiological Process: transcription, DNA-dependent; positive regulation of transcription from RNA polymerase II promoter; cellular lipid metabolic process |
| UniProt Protein Details: | |
| NCBI Summary: | The protein encoded by this gene is a nuclear transcriptional co-activator for peroxisome proliferator activated receptor alpha. The encoded protein contains a zinc finger and is a helicase that appears to be part of the peroxisome proliferator activated receptor alpha interacting complex. This gene is a member of the DNA2/NAM7 helicase gene family. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008] |
| UniProt Code: | Q9BYK8 |
| NCBI GenInfo Identifier: | 156105693 |
| NCBI Gene ID: | 85441 |
| NCBI Accession: | NP_001032412.2 |
| UniProt Secondary Accession: | Q9BYK8,Q3C2G2, Q4VXQ1, Q8TEF3, Q96ND3, Q9C094 |
| UniProt Related Accession: | Q9BYK8 |
| Molecular Weight: | 294,651 Da |
| NCBI Full Name: | helicase with zinc finger domain 2 isoform 1 |
| NCBI Synonym Full Names: | helicase with zinc finger 2, transcriptional coactivator |
| NCBI Official Symbol: | HELZ2 |
| NCBI Official Synonym Symbols: | PDIP-1; PRIC285 |
| NCBI Protein Information: | helicase with zinc finger domain 2; PDIP1; PRIC complex; ATP-dependent helicase PRIC285; PPARG-DBD-interacting protein 1; PPAR gamma DBD-interacting protein 1; PPAR-gamma DBD-interacting protein 1; PPAR-alpha-interacting complex protein 285; PPARgamma-DNA |
| UniProt Protein Name: | Helicase with zinc finger domain 2 |
| UniProt Synonym Protein Names: | ATP-dependent helicase PRIC285; Helicase with zinc finger 2, transcriptional coactivator; PPAR-alpha-interacting complex protein 285; PPAR-gamma DNA-binding domain-interacting protein 1; PDIP1; PPAR-gamma DBD-interacting protein 1; Peroxisomal proliferator-activated receptor A-interacting complex 285 kDa protein |
| Protein Family: | Helicase with zinc finger domain |
| UniProt Gene Name: | HELZ2 |
| UniProt Entry Name: | HELZ2_HUMAN |
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