HECW2 Antibody (PACO03044)
- SKU:
- PACO03044
- Product Type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- ELISA
- Applications:
- WB
- Antibody Type:
- Polyclonal Antibody
- Conjugation:
- Unconjugated
Description
| Antibody Name: | HECW2 Antibody |
| Antibody SKU: | PACO03044 |
| Size: | 50ug |
| Host Species: | Rabbit |
| Tested Applications: | ELISA, WB |
| Recommended Dilutions: | WB:1:500-1:2000 |
| Species Reactivity: | Human |
| Immunogen: | synthesized peptide derived from the Internal region of human NEDL2. |
| Form: | Liquid |
| Storage Buffer: | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Purification Method: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
| Synonyms: | HECW2; KIAA1301; NEDL2; E3 ubiquitin-protein ligase HECW2; HECT; C2 and WW domain-containing protein 2; NEDD4-like E3 ubiquitin-protein ligase 2 |
| UniProt Protein Function: | HECW2: E3 ubiquitin-protein ligase that mediates ubiquitination of TP73. Acts to stabilize TP73 and enhance activation of transcription by TP73. 2 isoforms of the human protein are produced by alternative splicing.Protein type: Ubiquitin ligase; EC 6.3.2.19; EC 6.3.2.-; Ligase; Ubiquitin conjugating systemChromosomal Location of Human Ortholog: 2q32.3Cellular Component: cytoplasm; nucleusMolecular Function: ubiquitin-protein ligase activityBiological Process: protein ubiquitination during ubiquitin-dependent protein catabolic process |
| UniProt Protein Details: | |
| NCBI Summary: | |
| UniProt Code: | Q9P2P5 |
| NCBI GenInfo Identifier: | 126215718 |
| NCBI Gene ID: | 57520 |
| NCBI Accession: | Q9P2P5.2 |
| UniProt Secondary Accession: | Q9P2P5,Q17RT5, Q68DF8, Q9NPS9, B8ZZB4 |
| UniProt Related Accession: | Q9P2P5 |
| Molecular Weight: | 135,905 Da |
| NCBI Full Name: | E3 ubiquitin-protein ligase HECW2 |
| NCBI Synonym Full Names: | HECT, C2 and WW domain containing E3 ubiquitin protein ligase 2 |
| NCBI Official Symbol: | HECW2 |
| NCBI Official Synonym Symbols: | NEDL2 |
| NCBI Protein Information: | E3 ubiquitin-protein ligase HECW2 |
| UniProt Protein Name: | E3 ubiquitin-protein ligase HECW2 |
| UniProt Synonym Protein Names: | HECT, C2 and WW domain-containing protein 2; NEDD4-like E3 ubiquitin-protein ligase 2 |
| Protein Family: | E3 ubiquitin-protein ligase |
| UniProt Gene Name: | HECW2 |
| UniProt Entry Name: | HECW2_HUMAN |
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