Description
| Product Name: | HE4/WFDC2 Monoclonal Antibody |
| Product Code: | CAB21953 |
| Reactivity: | Human |
| Applications: | Western blotting |
| Host Species: | Rabbit |
| Purification Method: | Affinity purification |
| Isotype: | IgG |
| Clone No: | ARC53195 |
| Reactivity: | Human |
| Tested Applications: | WB, ELISA |
| Key Applications: | Western blotting |
| Recommended Dilution: | WB 1:500-1:1000 |
| Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300, 0.05% BSA, 50% glycerol, pH7.3. |
| Positive Samples: | OVCAR3 |
| Cellular Location: | Secreted |
This gene encodes a protein that is a member of the WFDC domain family. The WFDC domain, or WAP Signature motif, contains eight cysteines forming four disulfide bonds at the core of the protein, and functions as a protease inhibitor in many family members. This gene is expressed in pulmonary epithelial cells, and was also found to be expressed in some ovarian cancers. The encoded protein is a small secretory protein, which may be involved in sperm maturation.
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 31-124 of human HE4/WFDC2 (NP_006094.3). |
| Sequence: | EKTGV CPELQ ADQNC TQECV SDSEC ADNLK CCSAG CATFC SLPND KEGSC PQVNI NFPQL GLCRD QCQVD SQCPG QMKCC RNGCG KVSCV TPNF |
| Synonyms: | HE4, WAP5, EDDM4, dJ461P17.6 |
| Calculated MW: | 13kDa |
| Observed MW: | 23kDa |