Description
Antibody Name: | HDDC3 Antibody (PACO38538) |
Antibody SKU: | PACO38538 |
Size: | 50ug |
Host Species: | Rabbit |
Tested Applications: | ELISA, WB, IHC |
Recommended Dilutions: | ELISA:1:2000-1:10000, WB:1:1000-1:5000, IHC:1:20-1:200 |
Species Reactivity: | Human, Mouse |
Immunogen: | Recombinant Human Guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase MESH1 protein (2-140AA) |
Form: | Liquid |
Storage Buffer: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 |
Purification Method: | >95%, Protein G purified |
Clonality: | Polyclonal |
Isotype: | IgG |
Conjugate: | Non-conjugated |
Western blot. All lanes: HDDC3 antibody at 2µg/ml + Mouse heart tissue. Secondary. Goat polyclonal to rabbit IgG at 1/10000 dilution. Predicted band size: 21, 16 kDa. Observed band size: 21 kDa. | |
Immunohistochemistry of paraffin-embedded human prostate cancer using PACO38538 at dilution of 1:100. |
Background: | ppGpp hydrolyzing enzyme involved in starvation response. |
Synonyms: | Guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase MESH1 (EC 3.1.7.2) (HD domain-containing protein 3) (Metazoan SpoT homolog 1) (MESH1) (Penta-phosphate guanosine-3'-pyrophosphohydrolase) ((ppGpp)ase), HDDC3, MESH1 |
UniProt Protein Function: | HDDC3: ppGpp hydrolyzing enzyme involved in starvation response. Belongs to the MESH1 family. 2 isoforms of the human protein are produced by alternative splicing.Protein type: EC 3.1.7.2Chromosomal Location of Human Ortholog: 15q26.1Molecular Function: guanosine-3',5'-bis(diphosphate) 3'-diphosphatase activity; metal ion bindingBiological Process: metabolic process |
UniProt Protein Details: | |
NCBI Summary: | |
UniProt Code: | Q8N4P3 |
NCBI GenInfo Identifier: | 38348360 |
NCBI Gene ID: | 374659 |
NCBI Accession: | NP_940929.1 |
UniProt Secondary Accession: | Q8N4P3 |
UniProt Related Accession: | Q8N4P3 |
Molecular Weight: | |
NCBI Full Name: | guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase MESH1 isoform 2 |
NCBI Synonym Full Names: | HD domain containing 3 |
NCBI Official Symbol: | HDDC3 |
NCBI Official Synonym Symbols: | MESH1; (ppGpp)ase |
NCBI Protein Information: | guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase MESH1 |
UniProt Protein Name: | Guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase MESH1 |
UniProt Synonym Protein Names: | HD domain-containing protein 3; Metazoan SpoT homolog 1; MESH1; Penta-phosphate guanosine-3'-pyrophosphohydrolase; (ppGpp)ase |
Protein Family: | |
UniProt Gene Name: | HDDC3 |
UniProt Entry Name: | MESH1_HUMAN |