HDAC6 Monoclonal Antibody
- SKU:
- CAB22169
- Product Type:
- Antibody
- Antibody Type:
- Monoclonal Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- WB
Description
| Product Name: | HDAC6 Monoclonal Antibody |
| Product Code: | CAB22169 |
| Reactivity: | Human |
| Applications: | Western blotting |
| Host Species: | Rabbit |
| Purification Method: | Affinity purification |
| Isotype: | IgG |
| Clone No: | ARC55934 |
| Reactivity: | Human |
| Tested Applications: | WB, ELISA |
| Key Applications: | Western blotting |
| Recommended Dilution: | WB 1:1000-1:5000 |
| Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300, 0.05% BSA, 50% glycerol, pH7.3. |
| Positive Samples: | K-562 |
| Cellular Location: | axon cytoplasm, caveola, centrosome, ciliary basal body, cytoplasm, cytosol, histone deacetylase complex, multivesicular body, nucleoplasm, nucleus, perinuclear region of cytoplasm |
Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. The protein encoded by this gene belongs to class II of the histone deacetylase/acuc/apha family. It contains an internal duplication of two catalytic domains which appear to function independently of each other. This protein possesses histone deacetylase activity and represses transcription.
| Immunogen: | A synthetic peptide corresponding to a sequence within amino acids 600-700 of human HDAC6 (NP_006035.2). |
| Sequence: | NGAAV VRPPG HHAEQ DAACG FCFFN SVAVA ARHAQ TISGH ALRIL IVDWD VHHGN GTQHM FEDDP SVLYV SLHRY DHGTF FPMGD EGASS QIGRA AGTGF T |
| Synonyms: | HD6, JM21, CPBHM, PPP1R90 |
| Calculated MW: | 131kDa |
| Observed MW: | 160kDa |
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