Description
Product Name: | HDAC2 Monoclonal Antibody |
Product Code: | CAB22426 |
Reactivity: | Human, Mouse, Rat |
Applications: | Western blotting, Immunohistochemistry, Immunofluorescence, Immunoprecipitation |
Host Species: | Rabbit |
Purification Method: | Affinity purification |
Isotype: | IgG |
Clone No: | ARC0105 |
Reactivity: | Human, Mouse, Rat |
Tested Applications: | WB, IHC-P, IF/ICC, IP, ELISA |
Key Applications: | Western blotting, Immunohistochemistry, Immunofluorescence, Immunoprecipitation |
Recommended Dilution: | WB 1:500-1:2000, IHC-P 1:50-1:200, IF/ICC 1:50-1:200, IP 1:100-1:500 |
Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide, 0.05% BSA, 50% glycerol, pH7.3. |
Positive Samples: | HeLa |
Cellular Location: | Cytoplasm, Nucleus |
This gene product belongs to the histone deacetylase family. Histone deacetylases act via the formation of large multiprotein complexes, and are responsible for the deacetylation of lysine residues at the N-terminal regions of core histones (H2A, H2B, H3 and H4). This protein forms transcriptional repressor complexes by associating with many different proteins, including YY1, a mammalian zinc-finger transcription factor. Thus, it plays an important role in transcriptional regulation, cell cycle progression and developmental events. Alternative splicing results in multiple transcript variants.
Immunogen: | A synthetic peptide corresponding to a sequence within amino acids 389-488 of human HDAC2 (Q92769). |
Sequence: | AVHED SGDED GEDPD KRISI RASDK RIACD EEFSD SEDEG EGGRR NVADH KKGAK KARIE EDKKE TEDKK TDVKE EDKSK DNSGE KTDTK GTKSE QLSNP |
Synonyms: | HD2, RPD3, YAF1, KDAC2 |
Calculated MW: | 55kDa |
Observed MW: | 60kDa |