Description
Antibody Name: | HCAR3/HCAR2 Antibody (PACO05630) |
Antibody SKU: | PACO05630 |
Size: | 50ug |
Host Species: | Rabbit |
Tested Applications: | ELISA, WB, IF |
Recommended Dilutions: | ELISA:1:10000, WB:1:500-1:2000, IF:1:200-1:1000 |
Species Reactivity: | Human, Mouse, Rat |
Immunogen: | Synthesized peptide derived from the C-terminal region of human HM74. |
Form: | Liquid |
Storage Buffer: | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
Purification Method: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
Clonality: | Polyclonal |
Isotype: | IgG |
Conjugate: | Non-conjugated |
Synonyms: | HCAR3; GPR109B; HCA3; HM74B; NIACR2; Hydroxycarboxylic acid receptor 3; G-protein coupled receptor 109B; G-protein coupled receptor HM74; G-protein coupled receptor HM74B; Niacin receptor 2; Nicotinic acid receptor 2; HCAR2; GPR109A; HCA2; |
UniProt Protein Function: | GPR109B: Receptor for 3-OH-octanoid acid mediates a negative feedback regulation of adipocyte lipolysis to counteract prolipolytic influences under conditions of physiological or pathological increases in beta-oxidation rates. Acts as a low affinity receptor for nicotinic acid. This pharmacological effect requires nicotinic acid doses that are much higher than those provided by a normal diet. Belongs to the G-protein coupled receptor 1 family. |
UniProt Protein Details: | Protein type:GPCR, family 1; Receptor, GPCR; Membrane protein, multi-pass; Membrane protein, integral Chromosomal Location of Human Ortholog: 12q24.31 Cellular Component: cell junction; integral to plasma membrane; plasma membrane |
UniProt Code: | P49019 |
NCBI GenInfo Identifier: | 519668680 |
NCBI Gene ID: | 8843 |
NCBI Accession: | P49019.3 |
UniProt Secondary Accession: | P49019,Q8NGE4, A8K4G5, B2R830, E9PI97, |
UniProt Related Accession: | P49019 |
Molecular Weight: | 44,478 Da |
NCBI Full Name: | Hydroxycarboxylic acid receptor 3 |
NCBI Synonym Full Names: | hydroxycarboxylic acid receptor 3 |
NCBI Official Symbol: | HCAR3 |
NCBI Official Synonym Symbols: | HCA3; HM74; PUMAG; Puma-g; GPR109B |
NCBI Protein Information: | hydroxycarboxylic acid receptor 3 |
UniProt Protein Name: | Hydroxycarboxylic acid receptor 3 |
UniProt Synonym Protein Names: | G-protein coupled receptor 109B; G-protein coupled receptor HM74; G-protein coupled receptor HM74B; Niacin receptor 2; Nicotinic acid receptor 2 |
Protein Family: | Hydroxycarboxylic acid receptor |
UniProt Gene Name: | HCAR3 |
UniProt Entry Name: | HCAR3_HUMAN |