HBG2 Polyclonal Antibody
- SKU:
- CAB7683
- Product Type:
- Antibody
- Antibody Type:
- Polyclonal Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- WB
Description
| Product Name: | HBG2 Polyclonal Antibody |
| Product Code: | CAB7683 |
| Reactivity: | Human |
| Applications: | Western blotting |
| Host Species: | Rabbit |
| Purification Method: | Affinity purification |
| Isotype: | IgG |
| Reactivity: | Human |
| Tested Applications: | WB, ELISA |
| Key Applications: | Western blotting |
| Recommended Dilution: | WB 1:100-1:500 |
| Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300, 50% glycerol, pH7.3. |
| Positive Samples: | K-562 |
| Cellular Location: | blood microparticle, cytosol, hemoglobin complex |
The gamma globin genes (HBG1 and HBG2) are normally expressed in the fetal liver, spleen and bone marrow. Two gamma chains together with two alpha chains constitute fetal hemoglobin (HbF) which is normally replaced by adult hemoglobin (HbA) at birth. In some beta-thalassemias and related conditions, gamma chain production continues into adulthood. The two types of gamma chains differ at residue 136 where glycine is found in the G-gamma product (HBG2) and alanine is found in the A-gamma product (HBG1). The former is predominant at birth. The order of the genes in the beta-globin cluster is: 5'- epsilon -- gamma-G -- gamma-A -- delta -- beta--3'.
| Immunogen: | A synthetic peptide corresponding to a sequence within amino acids 1-100 of human HBG2 (NP_000175.1). |
| Sequence: | MGHFT EEDKA TITSL WGKVN VEDAG GETLG RLLVV YPWTQ RFFDS FGNLS SASAI MGNPK VKAHG KKVLT SLGDA IKHLD DLKGT FAQLS ELHCD KLHVD |
| Synonyms: | TNCY, HBG-T1 |
| Calculated MW: | 16kDa |
| Observed MW: | 13kDa |
Related Products
HBG1/HBG2 Polyclonal Antibody
OverviewProduct Name:HBG1/HBG2 Polyclonal AntibodyProduct Code:CAB23436Reactivity:HumanApplications:Western blotting, Immunofluor
Doublecortin Polyclonal Antibody
OverviewProduct Name:Doublecortin Polyclonal AntibodyProduct Code:CAB0149Reactivity:Human, MouseApplications:Western blotting, Im
TULP1 Polyclonal Antibody
OverviewProduct Name:TULP1 Polyclonal AntibodyProduct Code:CAB10659Reactivity:HumanApplications:Western blotting
RHBDD1 Polyclonal Antibody
RHBDD1 Polyclonal AntibodyThe product page for this antibody is being prepared. If you have a question please don't hesitate to get in touch!