HAUS7 Antibody (PACO20813)
- SKU:
- PACO20813
- Product Type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- ELISA
- Applications:
- IHC
- Antibody Type:
- Polyclonal Antibody
- Conjugation:
- Unconjugated
Description
| Antibody Name: | HAUS7 Antibody (PACO20813) |
| Antibody SKU: | PACO20813 |
| Size: | 50ul |
| Host Species: | Rabbit |
| Tested Applications: | ELISA, IHC |
| Recommended Dilutions: | ELISA:1:2000-1:5000, IHC:1:25-1:100 |
| Species Reactivity: | Human |
| Immunogen: | Synthetic peptide of human HAUS7 |
| Form: | Liquid |
| Storage Buffer: | -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol |
| Purification Method: | Antigen affinity purification |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
 | The image on the left is immunohistochemistry of paraffin-embedded Human liver cancer tissue using PACO20813(HAUS7 Antibody) at dilution 1/30, on the right is treated with synthetic peptide. (Original magnification: x200). |
| Background: | This gene encodes a subunit of the augmin complex, which regulates centrosome and mitotic spindle integrity, and is necessary for the completion of cytokinesis. The encoded protein was identified by interaction with ubiquitin C-terminal hydrolase 37. Alternative splicing results in multiple transcript variants. |
| Synonyms: | HAUS augmin-like complex, subunit 7 |
| UniProt Protein Function: | HAUS7: Contributes to mitotic spindle assembly, maintenance of centrosome integrity and completion of cytokinesis as part of the HAUS augmin-like complex. Belongs to the HAUS7 family. 3 isoforms of the human protein are produced by alternative splicing.Protein type: Deoxyribonuclease; DNA-binding; EC 3.1.11.2Chromosomal Location of Human Ortholog: Xq28Cellular Component: centrosome; cytoplasm; cytosol; nucleolus; plasma membraneMolecular Function: thioesterase bindingBiological Process: centrosome organization and biogenesis; G2/M transition of mitotic cell cycle; spindle assembly |
| UniProt Protein Details: | |
| NCBI Summary: | This gene encodes a subunit of the augmin complex, which regulates centrosome and mitotic spindle integrity, and is necessary for the completion of cytokinesis. The encoded protein was identified by interaction with ubiquitin C-terminal hydrolase 37. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2012] |
| UniProt Code: | Q99871 |
| NCBI GenInfo Identifier: | 251757468 |
| NCBI Gene ID: | 55559 |
| NCBI Accession: | Q99871.3 |
| UniProt Secondary Accession: | Q99871,Q96HS8, Q9NP54, Q9UFH9, B4DUH6, D3DWT9 |
| UniProt Related Accession: | Q99871 |
| Molecular Weight: | 37,524 Da |
| NCBI Full Name: | HAUS augmin-like complex subunit 7 |
| NCBI Synonym Full Names: | HAUS augmin like complex subunit 7 |
| NCBI Official Symbol: | HAUS7 |
| NCBI Official Synonym Symbols: | UIP1; UCHL5IP |
| NCBI Protein Information: | HAUS augmin-like complex subunit 7 |
| UniProt Protein Name: | HAUS augmin-like complex subunit 7 |
| UniProt Synonym Protein Names: | 26S proteasome-associated UCH37-interacting protein 1; UCHL5-interacting protein; X-linked protein STS1769 |
| Protein Family: | HAUS augmin-like complex |
| UniProt Gene Name: | HAUS7 |
| UniProt Entry Name: | HAUS7_HUMAN |
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