Has2 Antibody (PACO27305)
- SKU:
- PACO27305
- Product Type:
- Antibody
- Reactivity:
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- ELISA
- Antibody Type:
- Polyclonal Antibody
- Conjugation:
- Unconjugated
Description
| Antibody Name: | Has2 Antibody (PACO27305) |
| Antibody SKU: | PACO27305 |
| Size: | 50ug |
| Host Species: | Rabbit |
| Tested Applications: | ELISA |
| Recommended Dilutions: | |
| Species Reactivity: | Mouse |
| Immunogen: | Recombinant Mouse Hyaluronan synthase 2 protein (67-374AA) |
| Form: | Liquid |
| Storage Buffer: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 |
| Purification Method: | >95%, Protein G purified |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
| Background: | Catalyzes the addition of GlcNAc or GlcUA monosaccharides to the nascent hyaluronan polymer. Therefore, it is essential to hyaluronan synthesis a major component of most extracellular matrices that has a structural role in tissues architectures and regulates cell adhesion, migration and differentiation. This is one of the isozymes catalyzing that reaction and it is particularly responsible for the synthesis of high molecular mass hyaluronan. Required for the transition of endocardial cushion cells into mesenchymal cells, a process crucial for heart development. May also play a role in vasculogenesis. High molecular mass hyaluronan also play a role in early contact inhibition a process which stops cell growth when cells come into contact with each other or the extracellular matrix. |
| Synonyms: | Hyaluronan synthase 2 (EC 2.4.1.212) (Hyaluronate synthase 2) (Hyaluronic acid, synthase 2) (HA synthase 2), Has2 |
| UniProt Protein Function: | HAS2: Plays a role in hyaluronan/hyaluronic acid (HA) synthesis. Expressed in fibroblasts. Belongs to the nodC/HAS family. |
| UniProt Protein Details: | Protein type:Membrane protein, integral; Membrane protein, multi-pass; Motility/polarity/chemotaxis; EC 2.4.1.212; Transferase Cellular Component: cytoplasm; integral to membrane; integral to plasma membrane; membrane Molecular Function:hyaluronan synthase activity; transferase activity; transferase activity, transferring glycosyl groups Biological Process: cell adhesion; extracellular polysaccharide biosynthetic process; hyaluronan biosynthetic process; hyaluronan metabolic process; positive regulation of cell migration; positive regulation of cell proliferation; positive regulation of keratinocyte migration; positive regulation of smooth muscle cell migration; vasculogenesis |
| UniProt Code: | P70312 |
| NCBI GenInfo Identifier: | |
| NCBI Gene ID: | 15117 |
| NCBI Accession: | NP_032242.3 |
| UniProt Secondary Accession: | P70312,P70411, Q62405, Q68EF7, |
| UniProt Related Accession: | P70312 |
| Molecular Weight: | 37.9 kDa |
| NCBI Full Name: | |
| NCBI Synonym Full Names: | hyaluronan synthase 2 |
| NCBI Official Symbol: | Has2 |
| NCBI Protein Information: | hyaluronan synthase 2 |
| UniProt Protein Name: | Hyaluronan synthase 2 |
| UniProt Synonym Protein Names: | Hyaluronate synthase 2; Hyaluronic acid synthase 2; HA synthase 2 |
| Protein Family: | Hyaluronan synthase |
| UniProt Gene Name: | Has2 |
| UniProt Entry Name: | HYAS2_MOUSE |
Related Products
Human HAS2(Hyaluronan synthase 2) ELISA Kit
system_update_altDatasheet - तकनीकी मैनुअलsystem_update_altMSDS - तकनीक
