Description
Product Name: | HAO1/GOX Monoclonal Antibody |
Product Code: | CAB22043 |
Reactivity: | Human, Mouse |
Applications: | Western blotting, Immunohistochemistry |
Host Species: | Rabbit |
Purification Method: | Affinity purification |
Isotype: | IgG |
Clone No: | ARC53722 |
Reactivity: | Human, Mouse |
Tested Applications: | WB, IHC-P, ELISA |
Key Applications: | Western blotting, Immunohistochemistry |
Recommended Dilution: | WB 1:1000-1:5000, IHC-P 1:50-1:200 |
Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300, 0.05% BSA, 50% glycerol, pH7.3. |
Positive Samples: | Mouse liver |
Cellular Location: | Peroxisome |
This gene is one of three related genes that have 2-hydroxyacid oxidase activity yet differ in encoded protein amino acid sequence, tissue expression and substrate preference. Subcellular location of the encoded protein is the peroxisome. Specifically, this gene is expressed primarily in liver and pancreas and the encoded protein is most active on glycolate, a two-carbon substrate. The protein is also active on 2-hydroxy fatty acids. The transcript detected at high levels in pancreas may represent an alternatively spliced form or the use of a multiple near-consensus upstream polyadenylation site.
Immunogen: | A synthetic peptide corresponding to a sequence within amino acids 1-100 of human HAO1/GOX (NP_060015.1). |
Sequence: | MLPRL ICIND YEQHA KSVLP KSIYD YYRSG ANDEE TLADN IAAFS RWKLY PRMLR NVAET DLSTS VLGQR VSMPI CVGAT AMQRM AHVDG ELATV RACQS |
Synonyms: | GO, GOX, GOX1, HAOX1 |
Calculated MW: | 41kDa |
Observed MW: | 41kDa |