H2-Ab1 Monoclonal Antibody

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SKU:
CAB24650
Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Reactivity:
Mouse
Host Species:
Rabbit
Isotype:
IgG
Applications:
WB
Applications:
IHC
Applications:
IF

Description

Product Name:H2-Ab1 Monoclonal Antibody
Product Code:CAB24650
Reactivity:Mouse
Applications:Western blotting, Immunohistochemistry, Immunofluorescence
Host Species:Rabbit
Purification Method:Affinity purification
Isotype:IgG
Clone No:ARC64051
Reactivity:Mouse
Tested Applications:WB, IHC-P, IF/ICC, ELISA
Key Applications:Western blotting, Immunohistochemistry, Immunofluorescence
Recommended Dilution:WB 1:2000-1:5000, IHC-P 1:100-1:500, IF/ICC 1:50-1:200
Storage Buffer:Store at -20°C. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300, 0.05% BSA, 50% glycerol, pH7.3.
Positive Samples:Mouse thymus, Mouse heart (Low expression control)
Cellular Location:cell surface, early endosome, external side of plasma membrane, Golgi apparatus, multivesicular body, plasma membrane

Enables several functions, including peptide antigen binding activity; protein antigen binding activity; and toxic substance binding activity. Involved in several processes, including B cell affinity maturation; cellular response to interferon-gamma; and positive regulation of T-helper 1 type immune response. Acts upstream of or within antigen processing and presentation of exogenous peptide antigen via MHC class II and immune response. Located in Golgi apparatus; endosome; and external side of plasma membrane. Is integral component of membrane. Part of MHC class II protein complex. Is expressed in lung; metanephros; and thymus primordium. Orthologous to human HLA-DQB2 (major histocompatibility complex, class II, DQ beta 2).

Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 31-219 of mouse H2-Ab1（NP_996988.2）.
Sequence:ERHFV YQFMG ECYFT NGTQR IRYVT RYIYN REEYV RYDSD VGEHR AVTEL GRPDA EYWNS QPEIL ERTRA ELDTV CRHNY EGPET HTSLR RLEQP NVVIS LSRTE ALNHH NTLVC SVTDF YPAKI KVRWF RNGQE ETVGV SSTQL IRNGD WTFQV LVMLE MTPRR GEVYT CHVEH PSLKS PITVE WRAQ
Synonyms:IAb, Ia2, Ia-2, Abeta, H-2Ab, H2-Ab, Rmcs1, I-Abeta
Calculated MW:30kDa
Observed MW:30kDa
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