GUF1 Antibody (PACO22361)
- SKU:
- PACO22361
- Product Type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- ELISA
- Applications:
- IHC
- Antibody Type:
- Polyclonal Antibody
- Conjugation:
- Unconjugated
Description
| Antibody Name: | GUF1 Antibody (PACO22361) |
| Antibody SKU: | PACO22361 |
| Size: | 100ul |
| Host Species: | Rabbit |
| Tested Applications: | ELISA, IHC |
| Recommended Dilutions: | ELISA:1:2000-1:10000, IHC:1:50-1:100 |
| Species Reactivity: | Human, Mouse |
| Immunogen: | Synthesized peptide derived from internal of human GUF1. |
| Form: | Liquid |
| Storage Buffer: | Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
| Purification Method: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
 | Immunohistochemistry analysis of paraffin-embedded human colon carcinoma tissue using GUF1 antibody. |
| Background: | Promotes mitochondrial protein synthesis. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Binds to mitochondrial ribosomes in a GTP-dependent manner By similarity. HAMAP-Rule MF_03137 |
| Synonyms: | GTP-binding protein GUF1 homolog; |
| UniProt Protein Function: | GUF1: Promotes mitochondrial protein synthesis. May act as a fidelity factor of the translation reaction, by catalyzing a one- codon backward translocation of tRNAs on improperly translocated ribosomes. Binds to mitochondrial ribosomes in a GTP-dependent manner. Belongs to the GTP-binding elongation factor family. LepA subfamily.Protein type: Mitochondrial; EC 3.6.5.-Chromosomal Location of Human Ortholog: 4p12Cellular Component: mitochondrial matrix; mitochondrial inner membraneMolecular Function: GTPase activity; GTP binding; ribosome bindingBiological Process: positive regulation of translation; translation |
| UniProt Protein Details: | |
| NCBI Summary: | |
| UniProt Code: | Q8N442 |
| NCBI GenInfo Identifier: | 157426893 |
| NCBI Gene ID: | 60558 |
| NCBI Accession: | NP_068746.2 |
| UniProt Secondary Accession: | Q8N442,Q5XKM8, Q9H710, Q9H8U4 |
| UniProt Related Accession: | Q8N442 |
| Molecular Weight: | 74,328 Da |
| NCBI Full Name: | translation factor GUF1, mitochondrial |
| NCBI Synonym Full Names: | GUF1 GTPase homolog (S. cerevisiae) |
| NCBI Official Symbol: | GUF1 |
| NCBI Official Synonym Symbols: | EF-4 |
| NCBI Protein Information: | translation factor GUF1, mitochondrial; GTPase GUF1; ribosomal back-translocase; elongation factor 4 homolog; GTPase of unknown function 1; GTP-binding protein GUF1 homolog |
| UniProt Protein Name: | Translation factor GUF1, mitochondrial |
| UniProt Synonym Protein Names: | Elongation factor 4 homolog; EF-4; GTPase GUF1; Ribosomal back-translocase |
| Protein Family: | Translation factor |
| UniProt Gene Name: | GUF1 |
| UniProt Entry Name: | GUF1_HUMAN |
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