Description
| Antibody Name: | GUF1 Antibody |
| Antibody SKU: | PACO04929 |
| Size: | 50ug |
| Host Species: | Rabbit |
| Tested Applications: | ELISA, IHC |
| Recommended Dilutions: | IHC:1:100-1:300 |
| Species Reactivity: | Human |
| Immunogen: | synthesized peptide derived from the Internal region of human GUF1. |
| Form: | Liquid |
| Storage Buffer: | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Purification Method: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
| Synonyms: | GUF1; Translation factor GUF1; mitochondrial; Elongation factor 4 homolog; EF-4; GTPase GUF1; Ribosomal back-translocase |
| UniProt Protein Function: | GUF1: Promotes mitochondrial protein synthesis. May act as a fidelity factor of the translation reaction, by catalyzing a one- codon backward translocation of tRNAs on improperly translocated ribosomes. Binds to mitochondrial ribosomes in a GTP-dependent manner. Belongs to the GTP-binding elongation factor family. LepA subfamily.Protein type: Mitochondrial; EC 3.6.5.-Chromosomal Location of Human Ortholog: 4p12Cellular Component: mitochondrial matrix; mitochondrial inner membraneMolecular Function: GTPase activity; GTP binding; ribosome bindingBiological Process: positive regulation of translation; translation |
| UniProt Protein Details: | |
| NCBI Summary: | |
| UniProt Code: | Q8N442 |
| NCBI GenInfo Identifier: | 157426893 |
| NCBI Gene ID: | 60558 |
| NCBI Accession: | NP_068746.2 |
| UniProt Secondary Accession: | Q8N442,Q5XKM8, Q9H710, Q9H8U4 |
| UniProt Related Accession: | Q8N442 |
| Molecular Weight: | 74,328 Da |
| NCBI Full Name: | translation factor GUF1, mitochondrial |
| NCBI Synonym Full Names: | GUF1 GTPase homolog (S. cerevisiae) |
| NCBI Official Symbol: | GUF1 |
| NCBI Official Synonym Symbols: | EF-4 |
| NCBI Protein Information: | translation factor GUF1, mitochondrial; GTPase GUF1; ribosomal back-translocase; elongation factor 4 homolog; GTPase of unknown function 1; GTP-binding protein GUF1 homolog |
| UniProt Protein Name: | Translation factor GUF1, mitochondrial |
| UniProt Synonym Protein Names: | Elongation factor 4 homolog; EF-4; GTPase GUF1; Ribosomal back-translocase |
| Protein Family: | Translation factor |
| UniProt Gene Name: | GUF1 |
| UniProt Entry Name: | GUF1_HUMAN |