Description
Antibody Name: | GUF1 Antibody |
Antibody SKU: | PACO04929 |
Size: | 50ug |
Host Species: | Rabbit |
Tested Applications: | ELISA, IHC |
Recommended Dilutions: | IHC:1:100-1:300 |
Species Reactivity: | Human |
Immunogen: | synthesized peptide derived from the Internal region of human GUF1. |
Form: | Liquid |
Storage Buffer: | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
Purification Method: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
Clonality: | Polyclonal |
Isotype: | IgG |
Conjugate: | Non-conjugated |
Synonyms: | GUF1; Translation factor GUF1; mitochondrial; Elongation factor 4 homolog; EF-4; GTPase GUF1; Ribosomal back-translocase |
UniProt Protein Function: | GUF1: Promotes mitochondrial protein synthesis. May act as a fidelity factor of the translation reaction, by catalyzing a one- codon backward translocation of tRNAs on improperly translocated ribosomes. Binds to mitochondrial ribosomes in a GTP-dependent manner. Belongs to the GTP-binding elongation factor family. LepA subfamily.Protein type: Mitochondrial; EC 3.6.5.-Chromosomal Location of Human Ortholog: 4p12Cellular Component: mitochondrial matrix; mitochondrial inner membraneMolecular Function: GTPase activity; GTP binding; ribosome bindingBiological Process: positive regulation of translation; translation |
UniProt Protein Details: | |
NCBI Summary: | |
UniProt Code: | Q8N442 |
NCBI GenInfo Identifier: | 157426893 |
NCBI Gene ID: | 60558 |
NCBI Accession: | NP_068746.2 |
UniProt Secondary Accession: | Q8N442,Q5XKM8, Q9H710, Q9H8U4 |
UniProt Related Accession: | Q8N442 |
Molecular Weight: | 74,328 Da |
NCBI Full Name: | translation factor GUF1, mitochondrial |
NCBI Synonym Full Names: | GUF1 GTPase homolog (S. cerevisiae) |
NCBI Official Symbol: | GUF1 |
NCBI Official Synonym Symbols: | EF-4 |
NCBI Protein Information: | translation factor GUF1, mitochondrial; GTPase GUF1; ribosomal back-translocase; elongation factor 4 homolog; GTPase of unknown function 1; GTP-binding protein GUF1 homolog |
UniProt Protein Name: | Translation factor GUF1, mitochondrial |
UniProt Synonym Protein Names: | Elongation factor 4 homolog; EF-4; GTPase GUF1; Ribosomal back-translocase |
Protein Family: | Translation factor |
UniProt Gene Name: | GUF1 |
UniProt Entry Name: | GUF1_HUMAN |