GTPBP3 Antibody (PACO09640)
- SKU:
- PACO09640
- Product Type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- ELISA
- Applications:
- WB
- Applications:
- IHC
- Antibody Type:
- Polyclonal Antibody
- Conjugation:
- Unconjugated
Description
| Antibody Name: | GTPBP3 Antibody (PACO09640) |
| Antibody SKU: | PACO09640 |
| Size: | 50ul |
| Host Species: | Rabbit |
| Tested Applications: | ELISA, WB, IHC |
| Recommended Dilutions: | |
| Species Reactivity: | Human, Mouse, Rat |
| Immunogen: | Human GTPBP3 |
| Form: | Liquid |
| Storage Buffer: | PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles. |
| Purification Method: | Antigen Affinity Purified |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
| Synonyms: | GTP binding protein 3 (mitochondrial);GTPBP3;FLJ14700;GTPBG3;MSS1;MTGP1;THDF1 ; |
| UniProt Protein Function: | GTPBP3: GTPase involved in the 5-carboxymethylaminomethyl modification (mnm(5)s(2)U34) of the wobble uridine base in mitochondrial tRNAs (Probable). Belongs to the Era/MnmE GTP-binding protein family. MnmE subfamily. 3 isoforms of the human protein are produced by alternative splicing. |
| UniProt Protein Details: | Chromosomal Location of Human Ortholog: 19p13.11 Cellular Component: mitochondrion; nucleus Molecular Function:GTPase activity; GTP binding Biological Process: tRNA modification Disease: Combined Oxidative Phosphorylation Deficiency 23 |
| NCBI Summary: | This locus encodes a GTP-binding protein. The encoded protein is localized to the mitochondria and may play a role in mitochondrial tRNA modification. Polymorphisms at this locus may be associated with severity of aminoglycoside-induced deafness, a disease associated with a mutation in the 12S rRNA. Alternatively spliced transcript variants encoding different isoforms have been described. [provided by RefSeq, Sep 2010] |
| UniProt Code: | Q969Y2 |
| NCBI GenInfo Identifier: | 313104112 |
| NCBI Gene ID: | 84705 |
| NCBI Accession: | Q969Y2.2 |
| UniProt Secondary Accession: | Q969Y2,Q8TCY6, Q8WUW9, Q969G4, Q9BX61, A6NFH1, A6NIG5 A6NKR4, A8K7B4, B7Z4V8, |
| UniProt Related Accession: | Q969Y2 |
| Molecular Weight: | 492 |
| NCBI Full Name: | tRNA modification GTPase GTPBP3, mitochondrial |
| NCBI Synonym Full Names: | GTP binding protein 3 (mitochondrial) |
| NCBI Official Symbol: | GTPBP3 |
| NCBI Official Synonym Symbols: | MSS1; MTGP1; THDF1; GTPBG3 |
| NCBI Protein Information: | tRNA modification GTPase GTPBP3, mitochondrial; mitochondrial GTP-binding protein 1 |
| UniProt Protein Name: | tRNA modification GTPase GTPBP3, mitochondrial |
| UniProt Synonym Protein Names: | GTP-binding protein 3; Mitochondrial GTP-binding protein 1 |
| Protein Family: | tRNA modification GTPase |
| UniProt Gene Name: | GTPBP3 |
| UniProt Entry Name: | GTPB3_HUMAN |
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