GTF3C5 Antibody (PACO57596)
- SKU:
- PACO57596
- Product Type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- ELISA
- Applications:
- IHC
- Antibody Type:
- Polyclonal Antibody
- Conjugation:
- Unconjugated
Description
| Antibody Name: | GTF3C5 Antibody (PACO57596) |
| Antibody SKU: | PACO57596 |
| Size: | 50ug |
| Host Species: | Rabbit |
| Tested Applications: | ELISA, IHC |
| Recommended Dilutions: | ELISA:1:2000-1:10000, IHC:1:20-1:200 |
| Species Reactivity: | Human |
| Immunogen: | Recombinant Human General transcription factor 3C polypeptide 5 protein (305-448AA) |
| Form: | Liquid |
| Storage Buffer: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, pH 7.4 |
| Purification Method: | >95%, Protein G purified |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
 | IHC image of PACO57596 diluted at 1:100 and staining in paraffin-embedded human brain tissue performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is detected by a biotinylated secondary antibody and visualized using an HRP conjugated SP system. |
| Background: | Involved in RNA polymerase III-mediated transcription. Integral, tightly associated component of the DNA-binding TFIIIC2 subcomplex that directly binds tRNA and virus-associated RNA promoters. |
| Synonyms: | General transcription factor 3C polypeptide 5 (TF3C-epsilon) (Transcription factor IIIC 63 kDa subunit) (TFIIIC 63 kDa subunit) (TFIIIC63) (Transcription factor IIIC subunit epsilon), GTF3C5 |
| UniProt Protein Function: | GTF3C5: Involved in RNA polymerase III-mediated transcription. Integral, tightly associated component of the DNA-binding TFIIIC2 subcomplex that directly binds tRNA and virus-associated RNA promoters. Belongs to the TFIIIC subunit 5 family. 3 isoforms of the human protein are produced by alternative splicing.Protein type: DNA-binding; Transcription initiation complexChromosomal Location of Human Ortholog: 9q34Cellular Component: nucleoplasm; transcription factor TFIIIC complexMolecular Function: DNA binding; protein bindingBiological Process: 5S class rRNA transcription; transcription from RNA polymerase III promoter; transcription, DNA-dependent; tRNA transcription from RNA polymerase III promoter |
| UniProt Protein Details: | |
| NCBI Summary: | |
| UniProt Code: | Q9Y5Q8 |
| NCBI GenInfo Identifier: | 47606222 |
| NCBI Gene ID: | 9328 |
| NCBI Accession: | Q9Y5Q8.2 |
| UniProt Secondary Accession: | Q9Y5Q8,Q5T7U2, Q5T7U3, Q8N2U7, Q8N857, Q96GD9, Q9H4P2 A6NI44, A6NJB9 |
| UniProt Related Accession: | Q9Y5Q8 |
| Molecular Weight: | 60,369 Da |
| NCBI Full Name: | General transcription factor 3C polypeptide 5 |
| NCBI Synonym Full Names: | general transcription factor IIIC subunit 5 |
| NCBI Official Symbol: | GTF3C5 |
| NCBI Official Synonym Symbols: | TFIIIC63; TFiiiC2-63; TFIIICepsilon |
| NCBI Protein Information: | general transcription factor 3C polypeptide 5 |
| UniProt Protein Name: | General transcription factor 3C polypeptide 5 |
| UniProt Synonym Protein Names: | TF3C-epsilon; Transcription factor IIIC 63 kDa subunit; TFIIIC 63 kDa subunit; TFIIIC63; Transcription factor IIIC subunit epsilon |
| Protein Family: | General transcription factor 3C polypeptide |
| UniProt Gene Name: | GTF3C5 |
| UniProt Entry Name: | TF3C5_HUMAN |
| Antibodies |
| GTF3C5 Antibody (PACO09637) |
| Secondary Antibody |
| Anti-HRP Goat Anti-Rabbit IgG (H+L) Antibody (CABS014) |
| Recommended Products |
| Anti-FITC Goat Anti-Rabbit IgG (H+L) Antibody (CABS011) |
| Anti-HRP-conjugated Beta Actin Antibody (CABC028) |
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