GTF2IRD1 Polyclonal Antibody
- SKU:
- CAB24506
- Product Type:
- Antibody
- Antibody Type:
- Polyclonal Antibody
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- WB
Description
| Product Name: | GTF2IRD1 Polyclonal Antibody |
| Product Code: | CAB24506 |
| Reactivity: | Rat |
| Applications: | Western blotting |
| Host Species: | Rabbit |
| Purification Method: | Affinity purification |
| Isotype: | IgG |
| Reactivity: | Rat |
| Tested Applications: | WB, ELISA |
| Key Applications: | Western blotting |
| Recommended Dilution: | WB 1:100-1:500 |
| Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300, 50% glycerol, pH7.3. |
| Positive Samples: | Rat liver |
| Cellular Location: | Nucleus |
The protein encoded by this gene contains five GTF2I-like repeats and each repeat possesses a potential helix-loop-helix (HLH) motif. It may have the ability to interact with other HLH-proteins and function as a transcription factor or as a positive transcriptional regulator under the control of Retinoblastoma protein. This gene plays a role in craniofacial and cognitive development and mutations have been associated with Williams-Beuren syndrome, a multisystem developmental disorder caused by deletion of multiple genes at 7q11.23. Alternative splicing results in multiple transcript variants.
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 660-890 of human GTF2IRD1 (NP_057412.1). |
| Sequence: | SLGFS PPALP PERDS GDPLV DESLK RQGFQ ENYDA RLSRI DIANT LREQV QDLFN KKYGE ALGIK YPVQV PYKRI KSNPG SVIIE GLPPG IPFRK PCTFG SQNLE RILAV ADKIK FTVTR PFQGL IPKPD EDDAN RLGEK VILRE QVKEL FNEKY GEALG LNRPV LVPYK LIRDS PDAVE VTGLP DDIPF RNPNT YDIHR LEKIL KAREH VRMVI INQLQ PFAEI CNDAK V |
| Synonyms: | GTF2IRD1, BEN, CREAM1, GTF3, MUSTRD1, RBAP2, WBS, WBSCR11, WBSCR12, hMusTRD1alpha1, GTF2I repeat domain containing 1 |
| Calculated MW: | 104kDa/106kDa/107kDa |
| Observed MW: | 130kDa |
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