Description
system_update_alt Datasheet
Product Name: | GSR Antibody |
Product Sku: | CPAB0192 |
Size: | 5μg |
Host Species: | Mouse |
Immunogen: | Anti-human GSR mAb, is derived from hybridization of mouse F myeloma cells with spleen cells from BALB/c mice immunized with recombinant human GSR amino acids 43-522 purified from Ecoli. |
Clone: | PAT11D10AT. |
Reactivity: | Human |
Applications: | Western Blot, ELISA |
Purification Method: | GSR antibody was purified from mouse ascitic fluids by protein-A affinity chromatography. |
Isotype: | IgG1 |
Background: | Glutathione reductase (GSR) belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family. The GSR enzyme is a homodimeric flavoprotein and has a role in maintaining glutathione (GSH) in its reduced form by catalyzing the reduction of glutathione disulfide (GSSG): GSSG + NADPH + H+ ->2GSH + NADP+. In the majority of eukaryotic cells, GSR upholds the ratio of [GSH] / [GSSG], and partakes in quite a few critical functions such as the detoxification of reactive oxygen species as well as protein and DNA biosynthesis. |
Synonyms: | Glutathione reductase mitochondrial, GR, GRase, GSR, GLUR, GRD1. |
Storage Buffer: | For periods up to 1 month store at 4°C, for longer periods of time, store at -20°C. Prevent freeze thaw cycles. |