GSK3β Polyclonal Antibody
- SKU:
- CAB21444
- Product Type:
- Antibody
- Antibody Type:
- Polyclonal Antibody
- Reactivity:
- Human
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- WB
Description
| Product Name: | GSK3β Polyclonal Antibody |
| Product Code: | CAB21444 |
| Reactivity: | Human, Rat |
| Applications: | Western blotting |
| Host Species: | Rabbit |
| Purification Method: | Affinity purification |
| Isotype: | IgG |
| Reactivity: | Human, Rat |
| Tested Applications: | WB, ELISA |
| Key Applications: | Western blotting |
| Recommended Dilution: | WB 1:500-1:1000 |
| Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300, 50% glycerol, pH7.3. |
| Positive Samples: | 293T, C6 |
| Cellular Location: | Cell membrane, Cytoplasm, Nucleus |
The protein encoded by this gene is a serine-threonine kinase belonging to the glycogen synthase kinase subfamily. It is a negative regulator of glucose homeostasis and is involved in energy metabolism, inflammation, ER-stress, mitochondrial dysfunction, and apoptotic pathways. Defects in this gene have been associated with Parkinson disease and Alzheimer disease.
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 350-420 of GSK3β (NP_001139628.1). |
| Sequence: | LPNGR DTPAL FNFTT QELSS NPPLA TILIP PHARI QAAAS TPTNA TAASD ANTGD RGQTN NAASA SASNS T |
| Synonyms: | GSK3B, glycogen synthase kinase-3 beta |
| Calculated MW: | 47kDa |
| Observed MW: | 47kDa |
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