GSK-3α/β Rabbit pAb
- SKU:
- CAB21167
- Product Type:
- Antibody
- Antibody Type:
- Polyclonal Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Applications:
- IHC
- Isotype:
- IgG
- Host Species:
- Rabbit
Description
| Product Name: | GSK-3α/β Rabbit pAb |
| Product Code: | CAB21167 |
| Application: | IHC |
| Reactivity: | Human, Mouse |
| Host Species: | Rabbit |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 253-368 of human GSK-3α/β (NP_063937.2). |
| Applications: | IHC |
| Recommended Dilution: | IHC 1:50 - 1:200 |
| Reactivity: | Human, Mouse |
| Positive Samples: | U-87MG, A-431, HeLa, B-cell, Mouse liver |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 253-368 of human GSK-3α/β (NP_063937.2). |
| Purification Method: | Affinity purification |
| Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Isotype: | IgG |
| Sequence: | DPDT AVLK LCDF GSAK QLVR GEPN VSYI CSRY YRAP ELIF GATD YTSS IDVW SAGC VLAE LLLG QPIF PGDS GVDQ LVEI IKVL GTPT REQI REMN PNYT EFKF PQIK AHPW TKVF |
| Gene ID: | 2931/ 2932 |
| Cellular Location: | Cell membrane, Cytoplasm, Nucleus |
| Calculated MW: | 46kDa/48kDa |
| Observed MW: | Refer to figures |
| Synonyms: | GSK3B, gsk-3β |
| Uniprot: | P49840 |
| Background: | The protein encoded by this gene is a serine-threonine kinase, belonging to the glycogen synthase kinase subfamily. It is involved in energy metabolism, neuronal cell development, and body pattern formation. Polymorphisms in this gene have been implicated in modifying risk of Parkinson disease, and studies in mice show that overexpression of this gene may be relevant to the pathogenesis of Alzheimer disease. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. |
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