GSK-3α/β Monoclonal Antibody (CAB22665)
- SKU:
- CAB22665
- Product Type:
- Antibody
- Antibody Type:
- Monoclonal Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- WB
- Applications:
- IP
Description
| Product Name: | GSK-3α/β Monoclonal Antibody |
| Product Code: | CAB22665 |
| Reactivity: | Human, Mouse, Rat |
| Applications: | Western blotting, Immunoprecipitation |
| Host Species: | Rabbit |
| Purification Method: | Affinity purification |
| Isotype: | IgG |
| Clone No: | ARC55345 |
| Reactivity: | Human, Mouse, Rat |
| Tested Applications: | WB, IP, ELISA |
| Key Applications: | Western blotting, Immunoprecipitation |
| Recommended Dilution: | WB 1:2000-1:20000, IP 1:50-1:200 |
| Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300, 0.05% BSA, 50% glycerol, pH7.3. |
| Cellular Location: | Cell membrane, Cytoplasm, Nucleus |
The protein encoded by this gene is a serine-threonine kinase, belonging to the glycogen synthase kinase subfamily. It is involved in energy metabolism, neuronal cell development, and body pattern formation. Polymorphisms in this gene have been implicated in modifying risk of Parkinson disease, and studies in mice show that overexpression of this gene may be relevant to the pathogenesis of Alzheimer disease. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
| Immunogen: | Recombinant protein of human GSK-3α/β（ NP_063937.2） |
| Sequence: | DPDTA VLKLC DFGSA KQLVR GEPNV SYICS RYYRA PELIF GATDY TSSID VWSAG CVLAE LLLGQ PIFPG DSGVD QLVEI IKVLG TPTRE QIREM NPNYT EFKFP QIKAH PWTKV F |
| Synonyms: | GSK3B, gsk-3β |
| Calculated MW: | 46kDa/48kDa |
| Observed MW: | Refer to figures |
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