GSDMD Monoclonal Antibody (CAB22602)

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SKU:
CAB22602
Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Reactivity:
Human
Reactivity:
Mouse
Reactivity:
Rat
Host Species:
Rabbit
Isotype:
IgG
Applications:
IF

Description

Product Name:GSDMD Monoclonal Antibody
Product Code:CAB22602
Reactivity:Human, Mouse, Rat
Applications:Immunofluorescence
Host Species:Rabbit
Purification Method:Affinity purification
Isotype:IgG
Clone No:ARC50990
Reactivity:Human, Mouse, Rat
Tested Applications:IF/ICC, ELISA
Key Applications:Immunofluorescence
Recommended Dilution:IF/ICC 1:50-1:200
Storage Buffer:Store at -20°C. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300, 0.05% BSA, 50% glycerol, pH7.3.
Cellular Location:Cytosol, Extracellular region, Extracellular space, NLRP3 inflammasome complex, Nucleoplasm, Plasma membrane

Gasdermin D is a member of the gasdermin family. Members of this family appear to play a role in regulation of epithelial proliferation. Gasdermin D has been suggested to act as a tumor suppressor. Alternatively spliced transcript variants have been described.

Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 346-484 of human GSDMD (NP_079012.3).
Sequence:DGPAG AVLEC LVLSS GMLVP ELAIP VVYLL GALTM LSETQ HKLLA EALES QTLLG PLELV GSLLE QSAPW QERST MSLPP GLLGN SWGEG APAWV LLDEC GLELG EDTPH VCWEP QAQGR MCALY ASLAL LSGLS QEPH
Synonyms:DF5L, DFNA5L, FKSG10, GSDMDC1
Calculated MW:53kDa
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