Description
Antibody Name: | GRK7 Antibody?FITC conjugated (PACO64117) |
Antibody SKU: | PACO64117 |
Size: | 50ul |
Host Species: | Rabbit |
Tested Applications: | ELISA |
Recommended Dilutions: | |
Species Reactivity: | Human |
Immunogen: | Recombinant Human Rhodopsin kinase protein (342-550AA) |
Form: | Liquid |
Storage Buffer: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, pH 7.4 |
Purification Method: | >95%, Antigen Affinity purified & Affinity purified |
Clonality: | Polyclonal |
Isotype: | IgG |
Conjugate: | FITC |
Background: | Retina-specific kinase involved in the shutoff of the photoresponse and adaptation to changing light conditions via cone opsin phosphorylation, including rhodopsin (RHO). |
Synonyms: | Rhodopsin kinase (EC 2.7.11.14) (G protein-coupled receptor kinase 7) (G protein-coupled receptor kinase GRK7), GRK7, GPRK7 |
UniProt Protein Function: | GRK7: Retina-specific kinase involved in the shutoff of the photoresponse and adaptation to changing light conditions via cone opsin phosphorylation, including rhodopsin (RHO). Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. GPRK subfamily. |
UniProt Protein Details: | Protein type:EC 2.7.11.14; Kinase, protein; Protein kinase, AGC; Protein kinase, Ser/Thr (non-receptor); EC 2.7.11.16; AGC group; GRK family; GRK subfamily Chromosomal Location of Human Ortholog: 3q24 Molecular Function:rhodopsin kinase activity Biological Process: protein amino acid autophosphorylation; regulation of rhodopsin mediated signaling |
NCBI Summary: | This gene encodes a member of the guanine nucleotide-binding protein (G protein)-coupled receptor kinase subfamily of the Ser/Thr protein kinase family. It is specifically expressed in the retina and the encoded protein has been shown to phosphorylate cone opsins and initiate their deactivation. [provided by RefSeq, Jul 2008] |
UniProt Code: | Q8WTQ7 |
NCBI GenInfo Identifier: | 21263659 |
NCBI Gene ID: | 131890 |
NCBI Accession: | Q8WTQ7.1 |
UniProt Related Accession: | Q8WTQ7 |
Molecular Weight: | 62,212 Da |
NCBI Full Name: | Rhodopsin kinase |
NCBI Synonym Full Names: | G protein-coupled receptor kinase 7 |
NCBI Official Symbol: | GRK7 |
NCBI Official Synonym Symbols: | GPRK7 |
NCBI Protein Information: | rhodopsin kinase |
UniProt Protein Name: | Rhodopsin kinase |
UniProt Synonym Protein Names: | G protein-coupled receptor kinase 7; G protein-coupled receptor kinase GRK7 |
Protein Family: | Rhodopsin kinase |
UniProt Gene Name: | GRK7 |
UniProt Entry Name: | GRK7_HUMAN |