GRID2IP Antibody (PACO45866)
- SKU:
- PACO45866
- Product Type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- ELISA
- Applications:
- IHC
- Applications:
- IF
- Antibody Type:
- Polyclonal Antibody
- Conjugation:
- Unconjugated
Description
| Antibody Name: | GRID2IP Antibody (PACO45866) |
| Antibody SKU: | PACO45866 |
| Size: | 50ug |
| Host Species: | Rabbit |
| Tested Applications: | ELISA, IHC, IF |
| Recommended Dilutions: | ELISA:1:2000-1:10000, IHC:1:20-1:200, IF:1:50-1:200 |
| Species Reactivity: | Human |
| Immunogen: | Recombinant Human Delphilin protein (35-156AA) |
| Form: | Liquid |
| Storage Buffer: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 |
| Purification Method: | >95%, Protein G purified |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
 | Immunohistochemistry of paraffin-embedded human kidney tissue using PACO45866 at dilution of 1:100. |
 | Immunofluorescent analysis of MCF-7 cells using PACO45866 at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L). |
 | Immunofluorescent analysis of HepG2 cells using PACO45866 at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L). |
| Background: | Postsynaptic scaffolding protein at the parallel fiber-Purkinje cell synapse, where it may serve to link GRID2 with actin cytoskeleton and various signaling molecules. |
| Synonyms: | Delphilin (Glutamate receptor, ionotropic, delta 2-interacting protein 1), GRID2IP |
| UniProt Protein Function: | GRID2IP: Postsynaptic scaffolding protein at the parallel fiber- Purkinje cell synapse, where it may serve to link GRID2 with actin cytoskeleton and various signaling molecules.Protein type: Adaptor/scaffoldChromosomal Location of Human Ortholog: 7p22.1 |
| UniProt Protein Details: | |
| NCBI Summary: | Glutamate receptor delta-2 (GRID2; MIM 602368) is predominantly expressed at parallel fiber-Purkinje cell postsynapses and plays crucial roles in synaptogenesis and synaptic plasticity. GRID2IP1 interacts with GRID2 and may control GRID2 signaling in Purkinje cells (Matsuda et al., 2006 [PubMed 16835239]).[supplied by OMIM, Mar 2008] |
| UniProt Code: | A4D2P6 |
| NCBI GenInfo Identifier: | 223278403 |
| NCBI Gene ID: | 392862 |
| NCBI Accession: | NP_001138590.1 |
| UniProt Secondary Accession: | A4D2P6 |
| UniProt Related Accession: | A4D2P6 |
| Molecular Weight: | 132,276 Da |
| NCBI Full Name: | delphilin |
| NCBI Synonym Full Names: | Grid2 interacting protein |
| NCBI Official Symbol: | GRID2IP |
| NCBI Official Synonym Symbols: | DELPHILIN |
| NCBI Protein Information: | delphilin |
| UniProt Protein Name: | Delphilin |
| UniProt Synonym Protein Names: | Glutamate receptor, ionotropic, delta 2-interacting protein 1 |
| Protein Family: | Delphilin |
| UniProt Gene Name: | GRID2IP |
| UniProt Entry Name: | GRD2I_HUMAN |
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