GRAMD4 Antibody (PACO48662)
- SKU:
- PACO48662
- Product Type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- ELISA
- Applications:
- WB
- Applications:
- IHC
- Antibody Type:
- Polyclonal Antibody
- Conjugation:
- Unconjugated
Description
| Antibody Name: | GRAMD4 Antibody (PACO48662) |
| Antibody SKU: | PACO48662 |
| Size: | 50ug |
| Host Species: | Rabbit |
| Tested Applications: | ELISA, WB, IHC |
| Recommended Dilutions: | ELISA:1:2000-1:10000, WB:1:500-1:5000, IHC:1:20-1:200 |
| Species Reactivity: | Human, Mouse |
| Immunogen: | Recombinant Human GRAM domain-containing protein 4 protein (23-161AA) |
| Form: | Liquid |
| Storage Buffer: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 |
| Purification Method: | >95%, Protein G purified |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
 | Western Blot. Positive WB detected in: Mouse brain tissue. All lanes: GRAMD4 antibody at 3.4µg/ml. Secondary. Goat polyclonal to rabbit IgG at 1/50000 dilution. Predicted band size: 67, 11 kDa. Observed band size: 67 kDa.. |
 | Western Blot. Positive WB detected in: MCF-7 whole cell lysate. All lanes: GRAMD4 antibody at 5µg/ml. Secondary. Goat polyclonal to rabbit IgG at 1/50000 dilution. Predicted band size: 67, 11 kDa. Observed band size: 67 kDa. |
 | Immunohistochemistry of paraffin-embedded human breast cancer using PACO48662 at dilution of 1:100. |
| Background: | Plays a role as a mediator of E2F1-induced apoptosis in the absence of p53/TP53. |
| Synonyms: | GRAM domain-containing protein 4 (Death-inducing protein), GRAMD4, DIP KIAA0767 |
| UniProt Protein Function: | DIP: Plays a role as a mediator of E2F1-induced apoptosis in the absence of p53/TP53. 2 isoforms of the human protein are produced by alternative splicing.Protein type: Apoptosis; Membrane protein, multi-pass; Membrane protein, integralChromosomal Location of Human Ortholog: 22q13.31 |
| UniProt Protein Details: | |
| NCBI Summary: | GRAMD4 is a mitochondrial effector of E2F1 (MIM 189971)-induced apoptosis (Stanelle et al., 2005 [PubMed 15565177]).[supplied by OMIM, Jan 2011] |
| UniProt Code: | Q6IC98 |
| NCBI GenInfo Identifier: | 120537317 |
| NCBI Gene ID: | 23151 |
| NCBI Accession: | BC129837 |
| UniProt Secondary Accession: | Q6IC98,Q68EN0, Q9UGE6, Q9Y4B9, A9IN51, A9IN57 |
| UniProt Related Accession: | Q6IC98 |
| Molecular Weight: | 10,923 Da |
| NCBI Full Name: | Homo sapiens GRAM domain containing 4, mRNA |
| NCBI Synonym Full Names: | GRAM domain containing 4 |
| NCBI Official Symbol: | GRAMD4 |
| NCBI Official Synonym Symbols: | DIP; dA59H18.1; dJ439F8.1 |
| NCBI Protein Information: | GRAM domain-containing protein 4 |
| UniProt Protein Name: | GRAM domain-containing protein 4 |
| UniProt Synonym Protein Names: | Death-inducing protein |
| Protein Family: | GRAM domain-containing protein |
| UniProt Gene Name: | GRAMD4 |
| UniProt Entry Name: | GRAM4_HUMAN |
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