Description
Antibody Name: | GPX5 Antibody (PACO48942) |
Antibody SKU: | PACO48942 |
Size: | 50ug |
Host Species: | Rabbit |
Tested Applications: | ELISA |
Recommended Dilutions: | |
Species Reactivity: | Pig |
Immunogen: | Recombinant Pig Epididymal secretory glutathione peroxidase protein (22-219AA) |
Form: | Liquid |
Storage Buffer: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 |
Purification Method: | >95%, Protein G purified |
Clonality: | Polyclonal |
Isotype: | IgG |
Conjugate: | Non-conjugated |
Background: | May constitute a glutathione peroxidase-like protective system against peroxide damage in sperm membrane lipids. Since the purified porcine enzyme has very little activity towards hydrogen peroxide or organic hydroperoxides the protective effect is not likely to be exerted by its enzymatic activity. Instead, may protect sperm from premature acrosome reaction in the epididymis by binding to lipid peroxides, which might otherwise interact with phospholipase A2 and induce the acrosome reaction. |
Synonyms: | Epididymal secretory glutathione peroxidase (EC 1.11.1.9) (Epididymis-specific glutathione peroxidase-like protein) (EGLP) (Glutathione peroxidase 5) (GPx-5) (GSHPx-5), GPX5 |
UniProt Protein Function: | May constitute a glutathione peroxidase-like protective system against peroxide damage in sperm membrane lipids. Since the purified porcine enzyme has very little activity towards hydrogen peroxide or organic hydroperoxides the protective effect is not likely to be exerted by its enzymatic activity. Instead, may protect sperm from premature acrosome reaction in the epididymis by binding to lipid peroxides, which might otherwise interact with phospholipase A2 and induce the acrosome reaction. |
UniProt Protein Details: | |
NCBI Summary: | |
UniProt Code: | O18994 |
NCBI GenInfo Identifier: | 47523090 |
NCBI Gene ID: | 396920 |
NCBI Accession: | NP_999051.1 |
UniProt Secondary Accession: | O18994 |
UniProt Related Accession: | O18994 |
Molecular Weight: | 24,936 Da |
NCBI Full Name: | epididymal secretory glutathione peroxidase |
NCBI Synonym Full Names: | |
NCBI Official Symbol: | GPX5 |
NCBI Official Synonym Symbols: | |
NCBI Protein Information: | epididymal secretory glutathione peroxidase |
UniProt Protein Name: | Epididymal secretory glutathione peroxidase |
UniProt Synonym Protein Names: | Epididymis-specific glutathione peroxidase-like protein; EGLP; Glutathione peroxidase 5; GPx-5; GSHPx-5 |
Protein Family: | Epididymal secretory glutathione peroxidase |
UniProt Gene Name: | GPX5 |
UniProt Entry Name: |