Description
Antibody Name: | GPR84 Antibody (PACO40638) |
Antibody SKU: | PACO40638 |
Size: | 50ug |
Host Species: | Rabbit |
Tested Applications: | ELISA, IF |
Recommended Dilutions: | ELISA:1:2000-1:10000, IF:1:50-1:200 |
Species Reactivity: | Human |
Immunogen: | Recombinant Human G-protein coupled receptor 84 protein (202-320AA) |
Form: | Liquid |
Storage Buffer: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 |
Purification Method: | >95%, Protein G purified |
Clonality: | Polyclonal |
Isotype: | IgG |
Conjugate: | Non-conjugated |
![]() | Immunofluorescent analysis of Hela cells using PACO40638 at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L). |
Background: | Receptor for medium-chain free fatty acid, (FFA) with carbon chain lengths of C9 to C14. Capric acid, (C10:0), undecanoic acid, (C11:0) and lauric acid, (C12:0) are the most potent agonists. Not activated by short-chain and long-chain saturated and unsaturated FFAs. Activation by medium-chain free fatty acid, is coupled to a pertussis toxin sensitive G(i/o) protein pathway. May have important roles in processes from fatty acid, metabolism to regulation of the immune system. |
Synonyms: | G-protein coupled receptor 84 (Inflammation-related G-protein coupled receptor EX33), GPR84, EX33 |
UniProt Protein Function: | GPR84: Receptor for medium-chain free fatty acid (FFA) with carbon chain lengths of C9 to C14. Capric acid (C10:0), undecanoic acid (C11:0) and lauric acid (C12:0) are the most potent agonists. Not activated by short-chain and long-chain saturated and unsaturated FFAs. Activation by medium-chain free fatty acid is coupled to a pertussis toxin sensitive G(i/o) protein pathway. May have important roles in processes from fatty acid metabolism to regulation of the immune system. Belongs to the G-protein coupled receptor 1 family.Protein type: Membrane protein, multi-pass; Motility/polarity/chemotaxis; GPCR, family 1; Receptor, GPCR; Membrane protein, integralChromosomal Location of Human Ortholog: 12q13.13Cellular Component: plasma membrane; integral to membrane; receptor complexMolecular Function: G-protein coupled receptor activityBiological Process: G-protein coupled receptor protein signaling pathway |
UniProt Protein Details: | |
NCBI Summary: | |
UniProt Code: | Q9NQS5 |
NCBI GenInfo Identifier: | 9966839 |
NCBI Gene ID: | 53831 |
NCBI Accession: | NP_065103.1 |
UniProt Secondary Accession: | Q9NQS5,B6V9G7 |
UniProt Related Accession: | Q9NQS5 |
Molecular Weight: | 43,705 Da |
NCBI Full Name: | G-protein coupled receptor 84 |
NCBI Synonym Full Names: | G protein-coupled receptor 84 |
NCBI Official Symbol: | GPR84 |
NCBI Official Synonym Symbols: | EX33; GPCR4 |
NCBI Protein Information: | G-protein coupled receptor 84; inflammation-related G protein-coupled receptor EX33; inflammation-related G-protein coupled receptor EX33 |
UniProt Protein Name: | G-protein coupled receptor 84 |
UniProt Synonym Protein Names: | Inflammation-related G-protein coupled receptor EX33 |
Protein Family: | G-protein coupled receptor |
UniProt Gene Name: | GPR84 |
UniProt Entry Name: | GPR84_HUMAN |