Description
| Antibody Name: | GPR161 Antibody (PACO09562) |
| Antibody SKU: | PACO09562 |
| Size: | 50ul |
| Host Species: | Rabbit |
| Tested Applications: | ELISA, WB |
| Recommended Dilutions: | |
| Species Reactivity: | Human, Mouse, Rat |
| Immunogen: | Human GPR161 |
| Form: | Liquid |
| Storage Buffer: | PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles. |
| Purification Method: | Antigen Affinity Purified |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
| Synonyms: | G protein-coupled receptor 161;GPR161;FLJ33952;RE2 ; |
| UniProt Protein Function: | GPR161: Orphan receptor. Plays a role in neurulation and lens development. Belongs to the G-protein coupled receptor 1 family. 3 isoforms of the human protein are produced by alternative splicing.Protein type: GPCR, family 1; Membrane protein, integral; Membrane protein, multi-pass; Receptor, GPCRChromosomal Location of Human Ortholog: 1q24.2Cellular Component: cilium; recycling endosomeMolecular Function: G-protein coupled receptor activityBiological Process: G-protein coupled receptor protein signaling pathway; positive regulation of cAMP biosynthetic process |
| UniProt Protein Details: | |
| NCBI Summary: | The protein encoded by this gene is an orphan G protein-coupled receptor whose ligand is unknown. This gene is overexpressed in triple-negative breast cancer, and disruption of this gene slows the proliferation of basal breast cancer cells. Therefore, this gene is a potential drug target for triple-negative breast cancer. [provided by RefSeq, Mar 2017] |
| UniProt Code: | Q8N6U8 |
| NCBI GenInfo Identifier: | 390190202 |
| NCBI Gene ID: | 23432 |
| NCBI Accession: | NP_001254538.1 |
| UniProt Secondary Accession: | Q8N6U8,O75963, Q5TGK0, Q5TGK1, Q5TGK2, B3KV34, B7Z5D7 B7Z5E8, B7Z5Z6, F5GXD6 |
| UniProt Related Accession: | Q8N6U8 |
| Molecular Weight: | 30.4kD |
| NCBI Full Name: | G-protein coupled receptor 161 isoform 1 |
| NCBI Synonym Full Names: | G protein-coupled receptor 161 |
| NCBI Official Symbol: | GPR161 |
| NCBI Official Synonym Symbols: | RE2 |
| NCBI Protein Information: | G-protein coupled receptor 161 |
| UniProt Protein Name: | G-protein coupled receptor 161 |
| UniProt Synonym Protein Names: | G-protein coupled receptor RE2 |
| Protein Family: | G-protein coupled receptor |
| UniProt Gene Name: | GPR161 |
| UniProt Entry Name: |