GPR132 Antibody (PACO06497)
- SKU:
- PACO06497
- Product Type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- NHP - Monkey
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- ELISA
- Applications:
- WB
- Applications:
- IF
- Antibody Type:
- Polyclonal Antibody
- Conjugation:
- Unconjugated
Description
| Antibody Name: | GPR132 Antibody (PACO06497) |
| Antibody SKU: | PACO06497 |
| Size: | 50ug |
| Host Species: | Rabbit |
| Tested Applications: | ELISA, WB, IF |
| Recommended Dilutions: | ELISA:1:5000, WB:1:500-1:2000, IF:1:200-1:1000 |
| Species Reactivity: | Human, Mouse, Monkey |
| Immunogen: | Synthesized peptide derived from the C-terminal region of human G2A. |
| Form: | Liquid |
| Storage Buffer: | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Purification Method: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
 | Western Blot analysis of various cells using G2A Polyclonal Antibody. |
 | Western Blot analysis of 293T cells using G2A Polyclonal Antibody. |
| Synonyms: | GPR132; G2A; Probable G-protein coupled receptor 132; G2 accumulation protein |
| UniProt Protein Function: | May be a receptor for oxidized free fatty acids derived from linoleic and arachidonic acids such as 9-hydroxyoctadecadienoic acid (9-HODE). Activates a G alpha protein, most likely G alpha(q). May be involved in apoptosis. Functions at the G2/M checkpoint to delay mitosis. May function as a sensor that monitors the oxidative states and mediates appropriate cellular responses such as secretion of paracrine signals and attenuation of proliferation. May mediate ths accumulation of intracellular inositol phosphates at acidic pH through proton-sensing activity. |
| UniProt Protein Details: | |
| NCBI Summary: | This gene encodes a member of the guanine nucleotide-binding protein (G protein)-coupled receptor (GPCR) superfamily. The receptors are seven-pass transmembrane proteins that respond to extracellular cues and activate intracellular signal transduction pathways. This protein was reported to be a receptor for lysophosphatidylcholine action, but PubMedID: 15653487 retracts this finding and instead suggests this protein to be an effector of lysophosphatidylcholine action. This protein may have proton-sensing activity and may be a receptor for oxidized free fatty acids. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2013] |
| UniProt Code: | Q9UNW8 |
| NCBI GenInfo Identifier: | 524579300 |
| NCBI Gene ID: | 29933 |
| NCBI Accession: | NP_001265623.1 |
| UniProt Secondary Accession: | Q9UNW8,Q9BSU2, A8K7X7, B4E144 |
| UniProt Related Accession: | Q9UNW8 |
| Molecular Weight: | 41,462 Da |
| NCBI Full Name: | probable G-protein coupled receptor 132 isoform 1 |
| NCBI Synonym Full Names: | G protein-coupled receptor 132 |
| NCBI Official Symbol: | GPR132 |
| NCBI Official Synonym Symbols: | G2A |
| NCBI Protein Information: | probable G-protein coupled receptor 132 |
| UniProt Protein Name: | Probable G-protein coupled receptor 132 |
| UniProt Synonym Protein Names: | G2 accumulation protein |
| Protein Family: | |
| UniProt Gene Name: | GPR132 |
| UniProt Entry Name: |
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