GPR1 Antibody (PACO56808)
- SKU:
- PACO56808
- Product Type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- ELISA
- Applications:
- IHC
- Applications:
- IF
- Antibody Type:
- Polyclonal Antibody
- Conjugation:
- Unconjugated
Description
| Antibody Name: | GPR1 Antibody (PACO56808) |
| Antibody SKU: | PACO56808 |
| Size: | 50ug |
| Host Species: | Rabbit |
| Tested Applications: | ELISA, IHC, IF |
| Recommended Dilutions: | ELISA:1:2000-1:10000, IHC:1:200-1:500, IF:1:50-1:200 |
| Species Reactivity: | Human |
| Immunogen: | Recombinant Human G-protein coupled receptor 1 protein (308-355AA) |
| Form: | Liquid |
| Storage Buffer: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, pH 7.4 |
| Purification Method: | >95%, Protein G purified |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
 | IHC image of PACO56808 diluted at 1:300 and staining in paraffin-embedded human liver cancer performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is detected by a biotinylated secondary antibody and visualized using an HRP conjugated SP system. |
 | Immunofluorescence staining of Hela cells with PACO56808 at 1:100, counter-stained with DAPI. The cells were fixed in 4% formaldehyde, permeabilized using 0.2% Triton X-100 and blocked in 10% normal Goat Serum. The cells were then incubated with the antibody overnight at 4°C. The secondary antibody was Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L). |
| Background: | Receptor for the inflammation-associated leukocyte chemoattractant chemerin/RARRES2 suggesting a role for this receptor in the regulation of inflammation. Can act as a coreceptor for HIV-1. |
| Synonyms: | G-protein coupled receptor 1, GPR1 |
| UniProt Protein Function: | GPR1: Receptor for the inflammation-associated leukocyte chemoattractant chemerin/RARRES2 suggesting a role for this receptor in the regulation of inflammation. Can act as a coreceptor for HIV-1. Belongs to the G-protein coupled receptor 1 family.Protein type: Receptor, GPCR; GPCR, family 1; Membrane protein, integral; Membrane protein, multi-passChromosomal Location of Human Ortholog: 2q33.3Cellular Component: neuron projection; integral to plasma membraneMolecular Function: G-protein coupled receptor activity; neuropeptide bindingBiological Process: synaptic transmission; G-protein signaling, coupled to cyclic nucleotide second messenger; G-protein coupled receptor protein signaling pathway; neuropeptide signaling pathway |
| UniProt Protein Details: | |
| NCBI Summary: | |
| UniProt Code: | P46091 |
| NCBI GenInfo Identifier: | 148228829 |
| NCBI Gene ID: | 2825 |
| NCBI Accession: | NP_001091669.1 |
| UniProt Secondary Accession: | P46091,Q53TR9, Q6NVX4, A5JUU6, A8K4L1 |
| UniProt Related Accession: | P46091 |
| Molecular Weight: | 41,431 Da |
| NCBI Full Name: | G-protein coupled receptor 1 |
| NCBI Synonym Full Names: | G protein-coupled receptor 1 |
| NCBI Official Symbol: | GPR1 |
| NCBI Official Synonym Symbols: | |
| NCBI Protein Information: | G-protein coupled receptor 1; probable G-protein coupled receptor 1 |
| UniProt Protein Name: | G-protein coupled receptor 1 |
| UniProt Synonym Protein Names: | |
| Protein Family: | G protein-coupled receptor |
| UniProt Gene Name: | GPR1 |
| UniProt Entry Name: | GPR1_HUMAN |
| Antibodies |
| GPR1 Antibody (PACO03913) |
| Secondary Antibody |
| Anti-HRP Goat Anti-Rabbit IgG (H+L) Antibody (CABS014) |
| Recommended Products |
| Anti-FITC Goat Anti-Rabbit IgG (H+L) Antibody (CABS011) |
| Anti-HRP-conjugated Beta Actin Antibody (CABC028) |
