GPI Monoclonal Antibody [PAT22G2AT] (CPAB0217)
![GPI Monoclonal Antibody [PAT22G2AT] (CPAB0217)](https://cdn11.bigcommerce.com/s-rd6ounxcu2/images/stencil/608x608/products/58443/63625/assay-genie-box-4__53625.1706535014.jpg?c=1 "GPI Monoclonal Antibody [PAT22G2AT] (CPAB0217)")
- SKU:
- CPAB0217
- Product Type:
- Antibody
- Antibody Type:
- Monoclonal Antibody
- Reactivity:
- Human
- Host Species:
- Mouse
- Isotype:
- IgG2a
- Clone:
- PAT22G2AT
- Applications:
- ELISA
- Applications:
- FC
![GPI Monoclonal Antibody [PAT22G2AT] (CPAB0217)](https://cdn11.bigcommerce.com/s-rd6ounxcu2/images/stencil/1280x1280/products/58443/63625/assay-genie-box-4__53625.1706535014.jpg?c=1&imbypass=on "GPI Monoclonal Antibody [PAT22G2AT] (CPAB0217)")
Description
system_update_alt Datasheet
| Product Name: | GPI Antibody |
| Product Sku: | CPAB0217 |
| Size: | 5μg |
| Host Species: | Mouse |
| Immunogen: | Anti-human GPI mAb, clone PAT22G2AT, is derived from hybridization of mouse F myeloma cells with spleen cells from BALB/c mice immunized with a recombinant human GPI protein 1-558 amino acids purified from Ecoli. |
| Clone: | PAT22G2AT. |
| Reactivity: | Human |
| Applications: | ELISA, Flow Cytometry |
| Purification Method: | GPI antibody was purified from mouse ascitic fluids by protein-A affinity chromatography. |
| Isotype: | IgG2a |
| Background: | Glucose-6-phosphate isomerase (GPI) is a part of the GPI family whose members encode multifunctional phosphoglucose isomerase proteins involved in energy pathways. GPI is a dimeric enzyme which catalyzes the reversible isomerization of glucose-6-phosphate and fructose-6-phosphate. Mammalian GPI also functions as a tumor-secreted cytokine and an angiogenic factor (AMF) which stimulates endothelial cell motility. In addition, GPI is a neurotrophic factor (Neuroleukin) for spinal and sensory neurons. GPI performs in different capacities inside and outside the cell. In the cytoplasm, GPI is involved in glycolysis and gluconeogenesis, while outside the cell it acts as a neurotrophic factor for spinal and sensory neurons. Defects in the GPI gene cause the nonspherocytic hemolytic anemia and a severe enzyme deficiency can be linked to hydrops fetalis, immediate neonatal death and neurological impairment. |
| Synonyms: | Glucose-6-phosphate isomerase, Phosphoglucose isomerase, Phosphohexose isomerase, Autocrine motility factor, Neuroleukin, Sperm antigen 36, GPI, PGI, PHI, AMF, NLK, SA-36, GNPI. |
| Storage Buffer: | For periods up to 1 month store at 4°C, for longer periods of time, store at -20°C. Prevent freeze thaw cycles. |
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