Description
| Antibody Name: | GPBP1 Antibody (PACO09543) |
| Antibody SKU: | PACO09543 |
| Size: | 50ul |
| Host Species: | Rabbit |
| Tested Applications: | ELISA, WB |
| Recommended Dilutions: | |
| Species Reactivity: | Human, Mouse, Rat |
| Immunogen: | Human GPBP1 |
| Form: | Liquid |
| Storage Buffer: | PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles. |
| Purification Method: | Antigen Affinity purified |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
| Synonyms: | GC-rich promoter binding protein 1;GPBP1;DKFZp761C169;GPBP;MGC126339;VASCULIN ; |
| UniProt Protein Function: | GPBP1: a novel vascular protein differentially expressed in human atherogenesis. Can be found in the plasma, thus it may be a possible marker for atherosclerosis.Protein type: Transcription factorChromosomal Location of Human Ortholog: 5q11.2Cellular Component: intracellular membrane-bound organelle; cytoplasm; nucleolus; plasma membraneMolecular Function: DNA binding; transcription factor activityBiological Process: transcription, DNA-dependent; positive regulation of transcription, DNA-dependent |
| UniProt Protein Details: | |
| NCBI Summary: | This gene was originally isolated by subtractive hybridization of cDNAs expressed in atherosclerotic plaques with a thrombus, and was found to be expressed only in vascular smooth muscle cells. However, a shorter splice variant was found to be more ubiquitously expressed. This protein is suggested to play a role in the development of atherosclerosis. Studies in mice suggest that it may also function as a GC-rich promoter-specific trans-activating transcription factor. Several alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Feb 2011] |
| UniProt Code: | Q86WP2 |
| NCBI GenInfo Identifier: | 291327500 |
| NCBI Gene ID: | 65056 |
| NCBI Accession: | NP_001120707.2 |
| UniProt Secondary Accession: | Q86WP2,Q6NSH6, Q9H0D4, Q9H785, Q9NSN4, A6NKW3 |
| UniProt Related Accession: | Q86WP2 |
| Molecular Weight: | 33,830 Da |
| NCBI Full Name: | vasculin isoform 3 |
| NCBI Synonym Full Names: | GC-rich promoter binding protein 1 |
| NCBI Official Symbol: | GPBP1 |
| NCBI Official Synonym Symbols: | GPBP; SSH6; VASCULIN |
| NCBI Protein Information: | vasculin |
| UniProt Protein Name: | Vasculin |
| UniProt Synonym Protein Names: | GC-rich promoter-binding protein 1; Vascular wall-linked protein |
| Protein Family: | Vasculin |
| UniProt Gene Name: | GPBP1 |
| UniProt Entry Name: | GPBP1_HUMAN |