GNG5 Antibody (PACO27089)
- SKU:
- PACO27089
- Product Type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- ELISA
- Applications:
- IHC
- Applications:
- IF
- Antibody Type:
- Polyclonal Antibody
- Conjugation:
- Unconjugated
Description
| Antibody Name: | GNG5 Antibody (PACO27089) |
| Antibody SKU: | PACO27089 |
| Size: | 50ug |
| Host Species: | Rabbit |
| Tested Applications: | ELISA, IHC, IF |
| Recommended Dilutions: | ELISA:1:2000-1:10000, IHC:1:20-1:200, IF:1:50-1:200 |
| Species Reactivity: | Human |
| Immunogen: | Recombinant Human Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-5 protein (2-65AA) |
| Form: | Liquid |
| Storage Buffer: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 |
| Purification Method: | >95%, Protein G purified |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
 | Immunohistochemistry of paraffin-embedded human liver cancer using PACO27089 at dilution of 1:100. |
 | Immunofluorescent analysis of PC-3 cells using PACO27089 at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L). |
 | Immunohistochemistry of paraffin-embedded human kidney tissue using PACO27089 at dilution of 1:100. |
| Background: | Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The β and γ chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. |
| Synonyms: | Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-5, GNG5, GNGT5 |
| UniProt Protein Function: | G-gamma 5: Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein- effector interaction. Belongs to the G protein gamma family.Protein type: G protein, heterotrimeric; G protein, heterotrimeric gamma; G protein; MitochondrialChromosomal Location of Human Ortholog: 1p22Cellular Component: membrane; plasma membraneMolecular Function: PDZ domain binding; protein binding |
| UniProt Protein Details: | |
| NCBI Summary: | G proteins are trimeric (alpha-beta-gamma) membrane-associated proteins that regulate flow of information from cell surface receptors to a variety of internal metabolic effectors. Interaction of a G protein with its activated receptor promotes exchange of GTP for GDP that is bound to the alpha subunit. The alpha-GTP complex dissociates from the beta-gamma heterodimer so that the subunits, in turn, may interact with and regulate effector molecules (Gilman, 1987 [PubMed 3113327]; summary by Ahmad et al., 1995) [PubMed 7606925].[supplied by OMIM, Nov 2010] |
| UniProt Code: | P63218 |
| NCBI GenInfo Identifier: | 52783599 |
| NCBI Gene ID: | 2787 |
| NCBI Accession: | P63218.3 |
| UniProt Secondary Accession: | P63218,P30670, Q5VX54, Q61015, B2R5A0 |
| UniProt Related Accession: | P63218 |
| Molecular Weight: | 7,318 Da |
| NCBI Full Name: | Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-5 |
| NCBI Synonym Full Names: | G protein subunit gamma 5 |
| NCBI Official Symbol: | GNG5 |
| NCBI Official Synonym Symbols: | |
| NCBI Protein Information: | guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-5 |
| UniProt Protein Name: | Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-5 |
| UniProt Synonym Protein Names: | |
| Protein Family: | |
| UniProt Gene Name: | GNG5 |
| UniProt Entry Name: | GBG5_HUMAN |
| Antibodies |
| GNG5 Antibody (PACO03908) |
| Secondary Antibody |
| Anti-HRP Goat Anti-Rabbit IgG (H+L) Antibody (CABS014) |
| Recommended Products |
| Anti-FITC Goat Anti-Rabbit IgG (H+L) Antibody (CABS011) |
| Anti-HRP-conjugated Beta Actin Antibody (CABC028) |
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