Description
| Antibody Name: | GNG5 Antibody |
| Antibody SKU: | PACO03908 |
| Size: | 50ug |
| Host Species: | Rabbit |
| Tested Applications: | ELISA, IF |
| Recommended Dilutions: | IF:1:200-1:1000 |
| Species Reactivity: | Human, Mouse, Rat |
| Immunogen: | synthesized peptide derived from the N-terminal region of human Ggamma 5. |
| Form: | Liquid |
| Storage Buffer: | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Purification Method: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
| Synonyms: | GNG5; GNGT5; Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-5 |
| UniProt Protein Function: | G-gamma 5: Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein- effector interaction. Belongs to the G protein gamma family.Protein type: G protein, heterotrimeric; G protein, heterotrimeric gamma; G protein; MitochondrialChromosomal Location of Human Ortholog: 1p22Cellular Component: membrane; plasma membraneMolecular Function: PDZ domain binding; protein binding |
| UniProt Protein Details: | |
| NCBI Summary: | G proteins are trimeric (alpha-beta-gamma) membrane-associated proteins that regulate flow of information from cell surface receptors to a variety of internal metabolic effectors. Interaction of a G protein with its activated receptor promotes exchange of GTP for GDP that is bound to the alpha subunit. The alpha-GTP complex dissociates from the beta-gamma heterodimer so that the subunits, in turn, may interact with and regulate effector molecules (Gilman, 1987 [PubMed 3113327]; summary by Ahmad et al., 1995) [PubMed 7606925].[supplied by OMIM, Nov 2010] |
| UniProt Code: | P63218 |
| NCBI GenInfo Identifier: | 52783599 |
| NCBI Gene ID: | 2787 |
| NCBI Accession: | P63218.3 |
| UniProt Secondary Accession: | P63218,P30670, Q5VX54, Q61015, B2R5A0 |
| UniProt Related Accession: | P63218 |
| Molecular Weight: | 7,318 Da |
| NCBI Full Name: | Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-5 |
| NCBI Synonym Full Names: | G protein subunit gamma 5 |
| NCBI Official Symbol: | GNG5 |
| NCBI Official Synonym Symbols: | |
| NCBI Protein Information: | guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-5 |
| UniProt Protein Name: | Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-5 |
| UniProt Synonym Protein Names: | |
| Protein Family: | |
| UniProt Gene Name: | GNG5 |
| UniProt Entry Name: | GBG5_HUMAN |