Description
Antibody Name: | GNG5 Antibody |
Antibody SKU: | PACO03908 |
Size: | 50ug |
Host Species: | Rabbit |
Tested Applications: | ELISA, IF |
Recommended Dilutions: | IF:1:200-1:1000 |
Species Reactivity: | Human, Mouse, Rat |
Immunogen: | synthesized peptide derived from the N-terminal region of human Ggamma 5. |
Form: | Liquid |
Storage Buffer: | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
Purification Method: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
Clonality: | Polyclonal |
Isotype: | IgG |
Conjugate: | Non-conjugated |
Synonyms: | GNG5; GNGT5; Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-5 |
UniProt Protein Function: | G-gamma 5: Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein- effector interaction. Belongs to the G protein gamma family.Protein type: G protein, heterotrimeric; G protein, heterotrimeric gamma; G protein; MitochondrialChromosomal Location of Human Ortholog: 1p22Cellular Component: membrane; plasma membraneMolecular Function: PDZ domain binding; protein binding |
UniProt Protein Details: | |
NCBI Summary: | G proteins are trimeric (alpha-beta-gamma) membrane-associated proteins that regulate flow of information from cell surface receptors to a variety of internal metabolic effectors. Interaction of a G protein with its activated receptor promotes exchange of GTP for GDP that is bound to the alpha subunit. The alpha-GTP complex dissociates from the beta-gamma heterodimer so that the subunits, in turn, may interact with and regulate effector molecules (Gilman, 1987 [PubMed 3113327]; summary by Ahmad et al., 1995) [PubMed 7606925].[supplied by OMIM, Nov 2010] |
UniProt Code: | P63218 |
NCBI GenInfo Identifier: | 52783599 |
NCBI Gene ID: | 2787 |
NCBI Accession: | P63218.3 |
UniProt Secondary Accession: | P63218,P30670, Q5VX54, Q61015, B2R5A0 |
UniProt Related Accession: | P63218 |
Molecular Weight: | 7,318 Da |
NCBI Full Name: | Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-5 |
NCBI Synonym Full Names: | G protein subunit gamma 5 |
NCBI Official Symbol: | GNG5 |
NCBI Official Synonym Symbols: | |
NCBI Protein Information: | guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-5 |
UniProt Protein Name: | Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-5 |
UniProt Synonym Protein Names: | |
Protein Family: | |
UniProt Gene Name: | GNG5 |
UniProt Entry Name: | GBG5_HUMAN |