Gnao1 Antibody (PACO27069)
- SKU:
- PACO27069
- Product Type:
- Antibody
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- ELISA
- Applications:
- WB
- Antibody Type:
- Polyclonal Antibody
- Conjugation:
- Unconjugated
Description
| Antibody Name: | Gnao1 Antibody (PACO27069) |
| Antibody SKU: | PACO27069 |
| Size: | 50ug |
| Host Species: | Rabbit |
| Tested Applications: | ELISA, WB |
| Recommended Dilutions: | ELISA:1:2000-1:10000, WB:1:500-1:5000 |
| Species Reactivity: | Mouse, Rat |
| Immunogen: | Recombinant Mouse Guanine nucleotide-binding protein G(o) subunit α protein (2-354AA) |
| Form: | Liquid |
| Storage Buffer: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 |
| Purification Method: | >95%, Protein G purified |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
 | Western Blot Positive WB detected in: Rat brain tissue, Mouse brain tissue All lanes: Gnao1 antibody at 3µg/ml Secondary Goat polyclonal to rabbit IgG at 1/50000 dilution Predicted band size: 41 kDa Observed band size: 41 kDa . |
| Background: | Guanine nucleotide-binding proteins (G proteins) are involved as modulators or transducers in various transmembrane signaling systems. Stimulated by RGS14. The G(o) protein function is not clear. |
| Synonyms: | Guanine nucleotide-binding protein G(o) subunit alpha, Gnao1, Gna0 Gnao |
| UniProt Protein Function: | G-alpha(o): Guanine nucleotide-binding proteins (G proteins) are involved as modulators or transducers in various transmembrane signaling systems. The G(o) protein function is not clear. Stimulated by RGS14. Interacts with RGS14. G proteins are composed of 3 units; alpha, beta and gamma. The alpha chain contains the guanine nucleotide binding site. Belongs to the G-alpha family. G(i/o/t/z) subfamily. 2 isoforms of the human protein are produced by alternative splicing.Protein type: G protein, heterotrimeric; G protein, heterotrimeric alpha G((i/o/t/z)); G proteinCellular Component: dendrite; heterotrimeric G-protein complex; membrane; myelin sheath; neuron projection; plasma membrane; protein complexMolecular Function: corticotropin-releasing hormone receptor 1 binding; G-protein beta/gamma-subunit binding; GTP binding; GTPase activating protein binding; GTPase activity; guanyl nucleotide binding; metabotropic serotonin receptor binding; metal ion binding; mu-type opioid receptor binding; nucleotide binding; protein binding; protein complex binding; signal transducer activityBiological Process: aging; cellular process; dopamine receptor signaling pathway; G-protein coupled receptor protein signaling pathway; G-protein signaling, coupled to cAMP nucleotide second messenger; locomotory behavior; negative regulation of calcium ion transport; positive regulation of GTPase activity; regulation of heart contraction; response to organic nitrogen; signal transduction |
| UniProt Protein Details: | |
| NCBI Summary: | |
| UniProt Code: | P18872 |
| NCBI GenInfo Identifier: | 164607137 |
| NCBI Gene ID: | 14681 |
| NCBI Accession: | NP_001106855.1 |
| UniProt Secondary Accession: | P18872,P18873 |
| UniProt Related Accession: | P18872 |
| Molecular Weight: | 40,036 Da |
| NCBI Full Name: | guanine nucleotide-binding protein G(o) subunit alpha isoform B |
| NCBI Synonym Full Names: | guanine nucleotide binding protein, alpha O |
| NCBI Official Symbol: | Gnao1 |
| NCBI Official Synonym Symbols: | Gnao; alphaO; Galphao; AW050213 |
| NCBI Protein Information: | guanine nucleotide-binding protein G(o) subunit alpha |
| UniProt Protein Name: | Guanine nucleotide-binding protein G(o) subunit alpha |
| UniProt Synonym Protein Names: | |
| Protein Family: | Guanine nucleotide-binding protein |
| UniProt Gene Name: | Gnao1 |
| UniProt Entry Name: | GNAO_MOUSE |
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