GMPR2 Antibody (PACO41226)
- SKU:
- PACO41226
- Product Type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- ELISA
- Antibody Type:
- Polyclonal Antibody
- Conjugation:
- Unconjugated
Description
| Antibody Name: | GMPR2 Antibody (PACO41226) |
| Antibody SKU: | PACO41226 |
| Size: | 50ug |
| Host Species: | Rabbit |
| Tested Applications: | ELISA |
| Recommended Dilutions: | |
| Species Reactivity: | Human |
| Immunogen: | Recombinant Human GMP reductase 2 protein (1-366AA) |
| Form: | Liquid |
| Storage Buffer: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 |
| Purification Method: | >95%, Protein G purified |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
| Background: | Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides. Plays a role in modulating cellular differentiation. |
| Synonyms: | GMP reductase 2 (GMPR 2) (EC 1.7.1.7) (Guanosine 5'-monophosphate oxidoreductase 2) (Guanosine monophosphate reductase 2), GMPR2 |
| UniProt Protein Function: | GMPR2: Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides. Plays a role in modulating cellular differentiation. Belongs to the IMPDH/GMPR family. 2 isoforms of the human protein are produced by alternative splicing.Protein type: EC 1.7.1.7; Nucleotide Metabolism - purine; OxidoreductaseChromosomal Location of Human Ortholog: 14q12Cellular Component: cytosolMolecular Function: GMP reductase activity; metal ion bindingBiological Process: nucleobase, nucleoside and nucleotide metabolic process; purine salvage; GMP metabolic process; purine base metabolic process |
| UniProt Protein Details: | |
| NCBI Summary: | |
| UniProt Code: | Q9P2T1 |
| NCBI GenInfo Identifier: | 50541952 |
| NCBI Gene ID: | 51292 |
| NCBI Accession: | NP_001002000.1 |
| UniProt Secondary Accession: | Q9P2T1,Q567T0, Q6IAJ8, Q86T14, D3DS66 |
| UniProt Related Accession: | Q9P2T1 |
| Molecular Weight: | 34,597 Da |
| NCBI Full Name: | GMP reductase 2 isoform 2 |
| NCBI Synonym Full Names: | guanosine monophosphate reductase 2 |
| NCBI Official Symbol: | GMPR2 |
| NCBI Official Synonym Symbols: | |
| NCBI Protein Information: | GMP reductase 2; guanosine 5'-monophosphate oxidoreductase 2; guanosine monophosphate reductase isolog |
| UniProt Protein Name: | GMP reductase 2 |
| UniProt Synonym Protein Names: | Guanosine 5'-monophosphate oxidoreductase 2; Guanosine monophosphate reductase 2 |
| Protein Family: | GMP reductase |
| UniProt Gene Name: | GMPR2 |
| UniProt Entry Name: | GMPR2_HUMAN |
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