Glutaredoxin 1 (GLRX) Monoclonal Antibody
- SKU:
- CAB23246
- Product Type:
- Antibody
- Antibody Type:
- Monoclonal Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- WB
Description
| Product Name: | Glutaredoxin 1 (GLRX) Monoclonal Antibody |
| Product Code: | CAB23246 |
| Reactivity: | Human, Mouse, Rat |
| Applications: | Western blotting |
| Host Species: | Rabbit |
| Purification Method: | Affinity purification |
| Isotype: | IgG |
| Clone No: | ARC59054 |
| Reactivity: | Human, Mouse, Rat |
| Tested Applications: | WB, ELISA |
| Key Applications: | Western blotting |
| Recommended Dilution: | WB 1:500-1:1000 |
| Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300, 0.05% BSA, 50% glycerol, pH7.3. |
| Positive Samples: | Jurkat, Mouse liver, Rat kidney |
| Cellular Location: | Cytoplasm |
This gene encodes a member of the glutaredoxin family. The encoded protein is a cytoplasmic enzyme catalyzing the reversible reduction of glutathione-protein mixed disulfides. This enzyme highly contributes to the antioxidant defense system. It is crucial for several signalling pathways by controlling the S-glutathionylation status of signalling mediators. It is involved in beta-amyloid toxicity and Alzheimer's disease. Multiple alternatively spliced transcript variants encoding the same protein have been identified.
| Immunogen: | A synthetic peptide corresponding to a sequence within amino acids 11-106 of human Glutaredoxin 1 (GLRX) (NP_002055.1). |
| Sequence: | QPGKV VVFIK PTCPY CRRAQ EILSQ LPIKQ GLLEF VDITA TNHTN EIQDY LQQLT GARTV PRVFI GKDCI GGCSD LVSLQ QSGEL LTRLK QIGAL Q |
| Synonyms: | GRX, GRX1 |
| Calculated MW: | 12kDa |
| Observed MW: | 12kDa |
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