Description
Product Name: | Glutaminase (GLS) Monoclonal Antibody |
Product Code: | CAB23189 |
Reactivity: | Human, Mouse, Rat |
Applications: | Western blotting, Immunofluorescence |
Host Species: | Rabbit |
Purification Method: | Affinity purification |
Isotype: | IgG |
Clone No: | ARC59924 |
Reactivity: | Human, Mouse, Rat |
Tested Applications: | WB, IF/ICC, ELISA |
Key Applications: | Western blotting, Immunofluorescence |
Recommended Dilution: | WB 1:1000-1:5000, IF/ICC 1:50-1:200 |
Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300, 0.05% BSA, 50% glycerol, pH7.3. |
Positive Samples: | 293T, Mouse ovary |
Cellular Location: | Cytoplasm, Mitochondrion, cytosol |
This gene encodes the K-type mitochondrial glutaminase. The encoded protein is an phosphate-activated amidohydrolase that catalyzes the hydrolysis of glutamine to glutamate and ammonia. This protein is primarily expressed in the brain and kidney plays an essential role in generating energy for metabolism, synthesizing the brain neurotransmitter glutamate and maintaining acid-base balance in the kidney. Alternate splicing results in multiple transcript variants.
Immunogen: | A synthesized peptide derived from human Glutaminase (GLS). |
Sequence: | Email for sequence |
Synonyms: | GAC, GAM, KGA, GLS1, AAD20, DEE71, GDPAG, CASGID, EIEE71 |
Calculated MW: | 73kDa |
Observed MW: | 58kDa/65kDa |