Glucagon Monoclonal Antibody (CAB23029)
- SKU:
- CAB23029
- Product Type:
- Antibody
- Antibody Type:
- Monoclonal Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- IHC
- Applications:
- IF
Description
| Product Name: | Glucagon Monoclonal Antibody |
| Product Code: | CAB23029 |
| Reactivity: | Human, Mouse, Rat |
| Applications: | Immunohistochemistry, Immunofluorescence |
| Host Species: | Rabbit |
| Purification Method: | Affinity purification |
| Isotype: | IgG |
| Clone No: | ARC56936 |
| Reactivity: | Human, Mouse, Rat |
| Tested Applications: | IHC-P, IF/ICC, ELISA |
| Key Applications: | Immunohistochemistry, Immunofluorescence |
| Recommended Dilution: | IHC-P 1:100-1:500, IF/ICC 1:100-1:500 |
| Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300, 0.05% BSA, 50% glycerol, pH7.3. |
| Cellular Location: | Secreted |
The protein encoded by this gene is actually a preproprotein that is cleaved into four distinct mature peptides. One of these, glucagon, is a pancreatic hormone that counteracts the glucose-lowering action of insulin by stimulating glycogenolysis and gluconeogenesis. Glucagon is a ligand for a specific G-protein linked receptor whose signalling pathway controls cell proliferation. Two of the other peptides are secreted from gut endocrine cells and promote nutrient absorption through distinct mechanisms. Finally, the fourth peptide is similar to glicentin, an active enteroglucagon.
| Immunogen: | A synthetic peptide corresponding to a sequence within amino acids 1-100 of human Glucagon (NP_002045.1). |
| Sequence: | MKSIY FVAGL FVMLV QGSWQ RSLQD TEEKS RSFSA SQADP LSDPD QMNED KRHSQ GTFTS DYSKY LDSRR AQDFV QWLMN TKRNR NNIAK RHDEF ERHAE |
| Synonyms: | GLP1, GLP2, GRPP, GLP-1 |
| Calculated MW: | 21kDa |
| Observed MW: | Refer to figures |
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