Description
| Product Name: | Glucagon Monoclonal Antibody |
| Product Code: | CAB11767 |
| Reactivity: | Mouse, Rat |
| Applications: | Immunohistochemistry, Immunofluorescence |
| Host Species: | Rabbit |
| Purification Method: | Affinity purification |
| Isotype: | IgG |
| Clone No: | ARC0382 |
| Reactivity: | Mouse, Rat |
| Tested Applications: | IHC-P, IF/ICC, ELISA |
| Key Applications: | Immunohistochemistry, Immunofluorescence |
| Recommended Dilution: | IHC-P 1:50-1:200, IF/ICC 1:50-1:200 |
| Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide, 0.05% BSA, 50% glycerol, pH7.3. |
| Cellular Location: | endoplasmic reticulum lumen, extracellular region, extracellular space |
The protein encoded by this gene is actually a preproprotein that is cleaved into four distinct mature peptides. One of these, glucagon, is a pancreatic hormone that counteracts the glucose-lowering action of insulin by stimulating glycogenolysis and gluconeogenesis. Glucagon is a ligand for a specific G-protein linked receptor whose signalling pathway controls cell proliferation. Two of the other peptides are secreted from gut endocrine cells and promote nutrient absorption through distinct mechanisms. Finally, the fourth peptide is similar to glicentin, an active enteroglucagon.
| Immunogen: | A synthesized peptide derived from human Glucagon |
| Sequence: | Email for sequence |
| Synonyms: | GLP1, GLP2, GRPP, GLP-1 |
| Calculated MW: | 21kDa |
| Observed MW: | Refer to figures |
