GLRA3 Antibody (PACO09486)
- SKU:
- PACO09486
- Product Type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- ELISA
- Applications:
- WB
- Antibody Type:
- Polyclonal Antibody
- Conjugation:
- Unconjugated
Description
| Antibody Name: | GLRA3 Antibody (PACO09486) |
| Antibody SKU: | PACO09486 |
| Size: | 50ul |
| Host Species: | Rabbit |
| Tested Applications: | ELISA, WB |
| Recommended Dilutions: | |
| Species Reactivity: | Human, Mouse, Rat |
| Immunogen: | Human GLRA3 |
| Form: | Liquid |
| Storage Buffer: | PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles. |
| Purification Method: | Antigen Affinity Purified |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
| Synonyms: | glycine receptor, α 3; |
| UniProt Protein Function: | GLRA3: The glycine receptor is a neurotransmitter-gated ion channel. Binding of glycine to its receptor increases the chloride conductance and thus produces hyperpolarization (inhibition of neuronal firing). Belongs to the ligand-gated ion channel (TC 1.A.9) family. Glycine receptor (TC 1.A.9.3) subfamily. GLRA3 sub- subfamily. 2 isoforms of the human protein are produced by alternative splicing.Protein type: Membrane protein, multi-pass; Transporter; Transporter, ion channel; Membrane protein, integralChromosomal Location of Human Ortholog: 4q34.1Cellular Component: postsynaptic membrane; integral to plasma membrane; plasma membrane; cell junctionMolecular Function: transmitter-gated ion channel activity; extracellular-glycine-gated chloride channel activity; glycine bindingBiological Process: transmembrane transport |
| UniProt Protein Details: | |
| NCBI Summary: | The GLRA3 gene encodes the alpha-3 subunit of the neuronal glycine receptor, a ligand-gated chloride channel composed of ligand-binding alpha and structural beta polypeptides (Kingsmore et al., 1994 [PubMed 7894176]).[supplied by OMIM] |
| UniProt Code: | O75311 |
| NCBI GenInfo Identifier: | 110347441 |
| NCBI Gene ID: | 8001 |
| NCBI Accession: | NP_006520.2 |
| UniProt Secondary Accession: | O75311,O75816, Q5D0E3, D3DP44 |
| UniProt Related Accession: | O75311, Q4W595, Q9UPF3 |
| Molecular Weight: | 53,800 Da |
| NCBI Full Name: | glycine receptor subunit alpha-3 isoform a |
| NCBI Synonym Full Names: | glycine receptor, alpha 3 |
| NCBI Official Symbol: | GLRA3 |
| NCBI Official Synonym Symbols: | GLRA3 |
| NCBI Protein Information: | glycine receptor subunit alpha-3; OTTHUMP00000194692; OTTHUMP00000194693; ligand gated ion channel; glycine receptor alpha 3 subunit; glycine receptor, alpha-3 polypeptide |
| UniProt Protein Name: | Glycine receptor subunit alpha-3 |
| UniProt Synonym Protein Names: | |
| Protein Family: | Glycine receptor |
| UniProt Gene Name: | GLRA3 |
| UniProt Entry Name: | GLRA3_HUMAN |
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