Description
| Product Name: | GLP2R Monoclonal Antibody |
| Product Code: | CAB22049 |
| Reactivity: | Human, Mouse, Rat |
| Applications: | Western blotting |
| Host Species: | Rabbit |
| Purification Method: | Affinity purification |
| Isotype: | IgG |
| Clone No: | ARC54969 |
| Reactivity: | Human, Mouse, Rat |
| Tested Applications: | WB, ELISA |
| Key Applications: | Western blotting |
| Recommended Dilution: | WB 1:1000-1:5000 |
| Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300, 0.05% BSA, 50% glycerol, pH7.3. |
| Positive Samples: | A-549, HeLa, Mouse brain, Rat brain, Rat liver |
| Cellular Location: | Cell membrane, Multi-pass membrane protein |
This gene encodes a G protein-coupled receptor that is closely related to the glucagon receptor and binds to glucagon-like peptide-2 (GLP2). Signalling through GLP2 stimulates intestinal growth and increases villus height in the small intestine, concomitant with increased crypt cell proliferation and decreased enterocyte apoptosis.
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 460-553 of human GLP2R (NP_004237.1). |
| Sequence: | SGCRA CVLGK DFRFL GKCPK KLSEG DGAEK LRKLQ PSLNS GRLLH LAMRG LGELG AQPQQ DHARW PRGSS LSECS EGDVT MANTM EEILE ESEI |
| Synonyms: | GLP2R |
| Calculated MW: | 63kDa |
| Observed MW: | 70kDa |