GLI2 Monoclonal Antibody

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SKU:
CAB23094
Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Reactivity:
Human
Reactivity:
Mouse
Reactivity:
Rat
Host Species:
Rabbit
Isotype:
IgG
Applications:
IHC
Applications:
IF

Description

Product Name:GLI2 Monoclonal Antibody
Product Code:CAB23094
Reactivity:Human, Mouse, Rat
Applications:Immunohistochemistry, Immunofluorescence
Host Species:Rabbit
Purification Method:Affinity purification
Isotype:IgG
Clone No:ARC58878
Reactivity:Human, Mouse, Rat
Tested Applications:IHC-P, IF/ICC, ELISA
Key Applications:Immunohistochemistry, Immunofluorescence
Recommended Dilution:IHC-P 1:50-1:200, IF/ICC 1:50-1:200
Storage Buffer:Store at -20°C. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300, 0.05% BSA, 50% glycerol, pH7.3.
Cellular Location:Nucleus

This gene encodes a protein which belongs to the C2H2-type zinc finger protein subclass of the Gli family. Members of this subclass are characterized as transcription factors which bind DNA through zinc finger motifs. These motifs contain conserved H-C links. Gli family zinc finger proteins are mediators of Sonic hedgehog (Shh) signaling and they are implicated as potent oncogenes in the embryonal carcinoma cell. The protein encoded by this gene localizes to the cytoplasm and activates patched Drosophila homolog (PTCH) gene expression. It is also thought to play a role during embryogenesis. The encoded protein is associated with several phenotypes- Greig cephalopolysyndactyly syndrome, Pallister-Hall syndrome, preaxial polydactyly type IV, postaxial polydactyly types A1 and B.

Immunogen:A synthesized peptide derived from human GLI2.
Sequence:Email for sequence
Synonyms:CJS, HPE9, PHS2, THP1, THP2
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